Date published: 2026-4-5

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Ammonium bicarbonate (CAS 1066-33-7)

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Alternate Names:
Ammonium hydrogen carbonate
Application:
Ammonium bicarbonate is a buffer applications such as lyophilization and matrix assisted laser desorption
CAS Number:
1066-33-7
Purity:
≥99%
Molecular Weight:
79.06
Molecular Formula:
NH4HCO3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Ammonium bicarbonate (NH4HCO3) is a chemical compound of significant interest in scientific research due to its unique properties and versatile applications across various disciplines. One of its primary mechanisms of action lies in its role as a leavening agent in food science and baking research. Ammonium bicarbonate decomposes upon heating, releasing carbon dioxide gas, which causes dough to rise and become airy during baking. This leavening action is particularly advantageous in the production of baked goods such as cookies, crackers, and pastries, where a light and fluffy texture is desired. Moreover, ammonium bicarbonate finds applications in analytical chemistry, where it is utilized as a reagent for the determination and quantification of certain analytes. Its reaction with specific functional groups, such as carboxylic acids, enables their derivatization and subsequent analysis via chromatographic or spectroscopic techniques. Additionally, research efforts have explored its potential in environmental science, where it serves as a source of ammonium ions in studies related to nitrogen cycling, soil fertility, and wastewater treatment. Furthermore, ammonium bicarbonate is utilized in the synthesis of specialty chemicals and pharmaceutical intermediates, owing to its role as a versatile precursor in organic transformations. Overall, ammonium bicarbonate continues to be a valuable compound in scientific investigations, owing to its diverse functionalities and broad utility in research applications spanning food science, analytical chemistry, environmental science, and organic synthesis.


Ammonium bicarbonate (CAS 1066-33-7) References

  1. Mechanism by which ammonium bicarbonate and ammonium sulfate inhibit mycotoxigenic fungi.  |  DePasquale, DA. and Montville, TJ. 1990. Appl Environ Microbiol. 56: 3711-7. PMID: 2082821
  2. Ammonium Bicarbonate Addition Improves the Detection of Proteins by Desorption Electrospray Ionization Mass Spectrometry.  |  Honarvar, E. and Venter, AR. 2017. J Am Soc Mass Spectrom. 28: 1109-1117. PMID: 28315234
  3. Ammonium Bicarbonate Inhibition of Mycotoxigenic Fungi and Spoilage Yeasts.  |  Depasquale, DA., et al. 1990. J Food Prot. 53: 324-328. PMID: 31018375
  4. Application of ammonium bicarbonate buffer as a smart microenvironmental pH regulator of immobilized cephalosporin C acylase catalysis in different reactors.  |  Chang, Y., et al. 2019. Biotechnol Prog. 35: e2846. PMID: 31099990
  5. Ammonium bicarbonate pretreatment of corn stalk for improved methane production via anaerobic digestion: Kinetic modeling.  |  He, C., et al. 2019. Bioresour Technol. 292: 122052. PMID: 31473038
  6. Development of Porous Epoxy Micro-Beads Using Ammonium Bicarbonate through a Single Epoxy Droplet in Corn Oil.  |  Leemsuthep, A., et al. 2021. Materials (Basel). 14: PMID: 33924997
  7. Ammonium Bicarbonate Significantly Accelerates the Microdroplet Reactions of Amines with Carbon Dioxide.  |  Feng, L., et al. 2021. Anal Chem. 93: 15775-15784. PMID: 34784192
  8. Transiting from the inhibited steady-state to the steady-state through the ammonium bicarbonate mediation in the anaerobic digestion of low-C/N-ratio food wastes.  |  Hao, T., et al. 2022. Bioresour Technol. 351: 127046. PMID: 35337997
  9. Tumor-triggered targeting ammonium bicarbonate liposomes for tumor multimodal therapy.  |  Chen, QB., et al. 2022. J Mater Chem B. 10: 5154-5164. PMID: 35666635

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Ammonium bicarbonate, 25 g

sc-207281
25 g
$31.00

Ammonium bicarbonate, 1 kg

sc-207281A
1 kg
$68.00

Ammonium bicarbonate, 10 kg

sc-207281B
10 kg
$194.00