Molecular structure of AMMC iodide
AMMC iodide
Alternate Names:
3-[2-(N,N-diethyl-N-methylammonium)ethyl]-7-methoxy-4-methylcoumarin iodide
Application:
AMMC iodide is a substrate for human CYP2D6 which is demethylated into a fluorescent derivative
Molecular Weight:
431.31
Molecular Formula:
C18H26INO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Human CYP2D6 demethylates AAMC iodide to its fluorescent derivative 3-[2-(N,N-diethyl-N-methylammonium)ethyl]-hydroxy-4-methylcoumarin.
AMMC iodide References
- Generation and validation of rapid computational filters for cyp2d6 and cyp3a4. | Ekins, S., et al. 2003. Drug Metab Dispos. 31: 1077-80. PMID: 12920160
- Cytochrome P450 2D6 enzyme neuroprotects against 1-methyl-4-phenylpyridinium toxicity in SH-SY5Y neuronal cells. | Mann, A. and Tyndale, RF. 2010. Eur J Neurosci. 31: 1185-93. PMID: 20345925
- Design, synthesis, and in vitro and in vivo characterization of new memantine analogs for Alzheimer's disease. | Turcu, AL., et al. 2022. Eur J Med Chem. 236: 114354. PMID: 35453065
Substrate of:
CYP2D6.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
AMMC iodide, 5 mg | sc-300196 | 5 mg | $709.00 |