AMJ2-C8 Whole Cell Lysate: sc-364366

The AMJ2-C8 Whole Cell Lysate originates from a murine alveolar macrophage cell line, which serves as a robust model for studying macrophage biology and their role in immune responses. This cell line was derived from the lung tissue of a specific strain of mice, providing a consistent and reproducible source of cellular material that includes a full array of proteins, RNA, and other macromolecules. In research, the AMJ2-C8 lysate is utilized to study the behavior of macrophages in various contexts, such as their response to pathogens, interaction with other immune cells, and their role in inflammation. The lysate provides a key comparative tool that allows researchers to dissect the signaling pathways and gene expression changes when exposed to different environmental stimuli or infectious agents. It is extensively used in proteomic studies where scientists analyze the protein content to understand the protein expression profiles and post-translational modifications specific to macrophages. Furthermore, the AMJ2-C8 lysate is crucial in experiments involving Western blotting, immunoprecipitation, and enzyme-linked immunosorbent assays, which help in identifying and quantifying specific proteins that are critical for macrophage functions. Through these studies, the lysate aids in advancing our understanding of macrophage physiology and their complex interactions within the immune system.