Amitriptyline Antibody (202): sc-57613

Amitriptyline Antibody (202) is a mouse monoclonal IgG1 antibody that detects amitriptyline in non-species reactive samples by enzyme-linked immunosorbent assay (ELISA). Amitriptyline is a tricyclic compound primarily known for its role as an antidepressant, affecting the reuptake of neurotransmitters such as serotonin and norepinephrine, which are crucial for mood regulation. Anti-amitriptyline antibody (202) provides researchers with a valuable tool for studying the pharmacodynamics and safety profiles of this important therapeutic agent. Amitriptyline′s function lies in alleviating symptoms of various depressive disorders, including endogenous depression and reactive depression, thereby improving patient quality of life. Additionally, amitriptyline is metabolized into nortriptyline and N-oxide amitriptylinoxide, which can also contribute to therapeutic effects. Understanding the metabolic pathways and interactions of amitriptyline is essential, as this highlights the potential for side effects, including cardiotoxicity and irreversible neural impairment in cases of overdose.