Date published: 2025-11-30

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Amisulpride-d5 (CAS 1216626-17-3)

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Alternate Names:
4-Amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide-d5
Application:
Amisulpride-d5 is a labeled Amisulpride
CAS Number:
1216626-17-3
Molecular Weight:
374.51
Molecular Formula:
C17H22D5N3O4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Amisulpride-d5 is a labeled Amisulpride. Amisulpride is an analogue of Sulpiride. Amisulpride-d5, a synthetic compound, has garnered interest in scientific research due to its potential applications. It shares similarities with Amisulpride in its interaction with dopamine receptors. Amisulpride is a dopamine receptor (D2DR/ D3DR) antagonist. The presence of deuterium, a heavier isotope of hydrogen, allows for the differentiated detection and quantification of the deuterated compound and its metabolites in biological matrices, using techniques such as mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy. This is particularly valuable in cokinetic studies, where understanding the absorption, distribution, metabolism, and excretion (ADME) of amisulpride is essential.


Amisulpride-d5 (CAS 1216626-17-3) References

  1. Development and validation of amisulpride in human plasma by HPLC coupled with tandem mass spectrometry and its application to a pharmacokinetic study.  |  Mogili, R., et al. 2011. Sci Pharm. 79: 583-99. PMID: 21886905
  2. Fast quantification of ten psychotropic drugs and metabolites in human plasma by ultra-high performance liquid chromatography tandem mass spectrometry for therapeutic drug monitoring.  |  Ansermot, N., et al. 2013. J Chromatogr A. 1292: 160-72. PMID: 23380367
  3. Comparison of conventional liquid chromatography-tandem mass spectrometry versus microflow liquid chromatography-tandem mass spectrometry within the framework of full method validation for simultaneous quantification of 40 antidepressants and neuroleptics in whole blood.  |  Steuer, AE., et al. 2015. J Chromatogr A. 1381: 87-100. PMID: 25596763
  4. Nontarget Screening Reveals Time Trends of Polar Micropollutants in a Riverbank Filtration System.  |  Albergamo, V., et al. 2019. Environ Sci Technol. 53: 7584-7594. PMID: 31244084
  5. Risk of Prolonged Corrected QT Interval With Amisulpride Therapy for Renal Function Management in Patients With Schizophrenia.  |  Chen, B., et al. 2020. J Clin Psychopharmacol. 40: 482-486. PMID: 32826486
  6. Nose-to-brain delivery of amisulpride-loaded lipid-based poloxamer-gellan gum nanoemulgel: In vitro and in vivo pharmacological studies.  |  Gadhave, D., et al. 2021. Int J Pharm. 607: 121050. PMID: 34454028
  7. Modeling and Simulation for Individualized Therapy of Amisulpride in Chinese Patients with Schizophrenia: Focus on Interindividual Variability, Therapeutic Reference Range and the Laboratory Alert Level.  |  Huang, S., et al. 2021. Drug Des Devel Ther. 15: 3903-3913. PMID: 34548782

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Amisulpride-d5, 1 mg

sc-217628
1 mg
$380.00