Molecular structure of (Aminomethyl)phosphonic acid, CAS Number: 1066-51-9
(Aminomethyl)phosphonic acid (CAS 1066-51-9)
Alternate Names:
AMPA
CAS Number:
1066-51-9
Purity:
≥98%
Molecular Weight:
111.04
Molecular Formula:
NH2CH2P(O)(OH)2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
(Aminomethyl)phosphonic acid is used in the synthesis of (acetylamino-methyl)-phosphonic acid through a reaction with acetic anhydride. It is used in the development of immobilized metal affinity chromatography columns based on organic-inorganic hybrid silica monoliths. This compound is a degradation product of glyphosate, a herbicide. Additionally, (Aminomethyl)phosphonic acid serves as a phosphonate agent in wastewater treatment. It inhibits the activity of enzymes involved in bacterial cell wall synthesis and energy metabolism, such as aminoglycoside-3′-phosphotransferase. Notably, (Aminomethyl)phosphonic acid exhibits neurotoxicity towards neuronal cells, with prolonged exposure leading to neuronal death.
(Aminomethyl)phosphonic acid (CAS 1066-51-9) References
- New methods for determination of glyphosate and (aminomethyl)phosphonic acid in water and soil. | Börjesson, E. and Torstensson, L. 2000. J Chromatogr A. 886: 207-16. PMID: 10950288
- Automated trace level determination of glyphosate and aminomethyl phosphonic acid in water by on-line anion-exchange solid-phase extraction followed by cation-exchange liquid chromatography and post-column derivatization. | Patsias, J., et al. 2001. J Chromatogr A. 932: 83-90. PMID: 11695871
- Determination of glyphosate and its metabolite, (aminomethyl)phosphonic acid, in serum using capillary electrophoresis. | Tomita, M., et al. 1991. J Chromatogr. 571: 324-30. PMID: 1810964
- High-performance liquid chromatographic determination of glyphosate and (aminomethyl)phosphonic acid in human serum after conversion into p-toluenesulphonyl derivatives. | Tomita, M., et al. 1991. J Chromatogr. 566: 239-43. PMID: 1885717
- Decontamination of aqueous glyphosate, (aminomethyl)phosphonic acid, and glufosinate solutions by electro-fenton-like process with Mn2+ as the catalyst. | Balci, B., et al. 2009. J Agric Food Chem. 57: 4888-94. PMID: 19438208
- Evaluation of Titanium Dioxide as a Binding Phase for the Passive Sampling of Glyphosate and Aminomethyl Phosphonic Acid in an Aquatic Environment. | Fauvelle, V., et al. 2015. Anal Chem. 87: 6004-9. PMID: 25978142
- PKMζ knockdown disrupts post-ischemic long-term potentiation via inhibiting postsynaptic expression of aminomethyl phosphonic acid receptors. | Cheng, N., et al. 2015. J Biomed Res. 29: 241-9. PMID: 26060448
- Environmental and health effects of the herbicide glyphosate. | Van Bruggen, AHC., et al. 2018. Sci Total Environ. 616-617: 255-268. PMID: 29117584
- A method for determining glyphosate and its metabolite aminomethyl phosphonic acid by gas chromatography-flame photometric detection. | Zhang, W., et al. 2019. J Chromatogr A. 1589: 116-121. PMID: 30587348
- [Rapid determination of glyphosate, aminomethyl phosphonic acid, glufosinate, and ethephon residues in environmental water by direct injection-ultra performance liquid chromatography-triple quadrupole mass spectrometry]. | He, S., et al. 2019. Se Pu. 37: 1179-1184. PMID: 31642270
- Dataset of compounds in glyphosate-free herbicides. | Seralini, GE. and Jungers, G. 2020. Data Brief. 33: 106564. PMID: 33304961
- Effects of low-concentration glyphosate and aminomethyl phosphonic acid on zebrafish embryo development. | Zhang, W., et al. 2021. Ecotoxicol Environ Saf. 226: 112854. PMID: 34619474
- The association between urinary glyphosate and aminomethyl phosphonic acid with biomarkers of oxidative stress among pregnant women in the PROTECT birth cohort study. | Eaton, JL., et al. 2022. Ecotoxicol Environ Saf. 233: 113300. PMID: 35158254
- Evaluation of the herbicide glyphosate, (aminomethyl)phosphonic acid, and glyphosate-based formulations for genotoxic activity using in vitro assays. | Smith-Roe, SL., et al. 2023. Environ Mol Mutagen. 64: 202-233. PMID: 36880770
Activator of:
GABA T-2, GluR-1, and oligophrenin-1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(Aminomethyl)phosphonic acid, 250 mg | sc-239227 | 250 mg | $61.00 |