Aminoglutethimide (CAS 125-84-8)
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Aminoglutethimide is a compound extensively studied in the field of biochemistry for its inhibitory effects on the enzymatic conversion of cholesterol to pregnenolone, a precursor to various steroid hormones. This mechanism is of particular interest in the investigation of biosynthetic pathways and the regulation of steroidogenesis. In research focusing on metabolic pathways, aminoglutethimide is used to understand the control and disruption of hormone synthesis at the molecular level. Additionally, the compound′s ability to inhibit aromatase, an enzyme that catalyzes the conversion of androgens to estrogens, makes it a subject of research in studies aiming to elucidate the role of estrogens in various biological processes. Aminoglutethimide also serves as a tool in endocrine research, where it is used to examine the feedback mechanisms in the hypothalamic-pituitary axis. Beyond its use in understanding hormone synthesis and action, aminoglutethimide is studied for its potential effects on cytochrome P450 enzymes, which are key players in chemical metabolism and the detoxification of xenobiotics.
Aminoglutethimide (CAS 125-84-8) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Aminoglutethimide, 1 g | sc-207280 | 1 g | $41.00 | |||
Aminoglutethimide, 5 g | sc-207280A | 5 g | $143.00 | |||
Aminoglutethimide, 25 g | sc-207280B | 25 g | $530.00 | |||
Aminoglutethimide, 100 g | sc-207280C | 100 g | $2020.00 |