Molecular structure of Amikacin sulfate salt, CAS Number: 149022-22-0
Amikacin sulfate salt (CAS 149022-22-0)
Application:
Amikacin sulfate salt is an antibacterial agent
CAS Number:
149022-22-0
Molecular Weight:
683.68
Molecular Formula:
C22H43N5O13•xH2SO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Amikacin sulfate salt is a compound extensively studied in the field of microbiology where it is used to investigate the efficacy of aminoglycosides against resistant bacterial strains. Researchers focus on its mechanism of action, which involves binding to the bacterial 30S ribosomal subunit, thereby inhibiting protein synthesis and leading to cell death. In biochemistry, amikacin sulfate salt is utilized to explore the transport and uptake of aminoglycosides into bacteria, as well as the induction of the SOS response—a bacterial mechanism to address DNA damage. Environmental scientists employ this compound in studies assessing the impact of antibiotics on microbial communities within wastewater treatment systems. Moreover, its role in inducing bacterial stress responses is a key area of research, which contributes to our broader understanding of antibiotic resistance mechanisms.
Amikacin sulfate salt (CAS 149022-22-0) References
- Comparison of intraosseous or intravenous infusion for delivery of amikacin sulfate to the tibiotarsal joint of horses. | Scheuch, BC., et al. 2002. Am J Vet Res. 63: 374-80. PMID: 11911572
- Effects of triamcinolone acetonide, sodium hyaluronate, amikacin sulfate, and mepivacaine hydrochloride, alone and in combination, on morphology and matrix composition of lipopolysaccharide-challenged and unchallenged equine articular cartilage explants. | Bolt, DM., et al. 2008. Am J Vet Res. 69: 861-7. PMID: 18593234
- Aerosol performance of large respirable particles of amikacin sulfate produced by spray and freeze drying techniques. | Padhi, BK., et al. 2009. Curr Drug Deliv. 6: 8-16. PMID: 19418951
- New luminol chemiluminescence reaction using diperiodatoargentate as oxidate for the determination of amikacin sulfate. | Yang, C., et al. 2010. Luminescence. 25: 36-42. PMID: 19585518
- Comparison of two tourniquets and determination of amikacin sulfate concentrations after metacarpophalangeal joint lavage performed simultaneously with intravenous regional limb perfusion in horses. | Alkabes, SB., et al. 2011. Am J Vet Res. 72: 613-9. PMID: 21529212
- Accumulation of amikacin in synovial fluid after regional limb perfusion of amikacin sulfate alone and in combination with ticarcillin/clavulanate in horses. | Zantingh, AJ., et al. 2014. Vet Surg. 43: 282-8. PMID: 24467593
- The Effect of Intravenous Regional Perfusion of the Distal Limb With Amikacin Sulfate on Wounds Healing by Second Intention in Horses. | Edwards-Milewski, ML., et al. 2016. Vet Surg. 45: 125-32. PMID: 26731602
- Effects of regional limb perfusion volume on concentrations of amikacin sulfate in synovial and interstitial fluid samples from anesthetized horses. | Godfrey, JL., et al. 2016. Am J Vet Res. 77: 582-8. PMID: 27227495
- The Effects of Mepivacaine Hydrochloride on Antimicrobial Activity and Mechanical Nociceptive Threshold During Amikacin Sulfate Regional Limb Perfusion in the Horse. | Colbath, AC., et al. 2016. Vet Surg. 45: 798-803. PMID: 27416788
- A novel luminol-based chemiluminescence method for the determination of amikacin sulfate in serum by using trivalent copper-periodate complex. | Hu, YF., et al. 2013. J Pharm Anal. 3: 360-366. PMID: 29403840
- Motility and fertility of frozen bull spermatozoa in tris-yolk and milk extenders containing amikacin sulfate. | Ahmad, K. and Foote, RH. 1985. J Dairy Sci. 68: 2083-6. PMID: 4044972
- Antimicrobial spectrum, pharmacology, adverse effects, and therapeutic use of amikacin sulfate. | Pien, FD. and Ho, PW. 1981. Am J Hosp Pharm. 38: 981-9. PMID: 7020413
- Effects of amikacin sulfate on the motility of stallion and bull spermatozoa at different temperatures and intervals of storage. | Arriola, J. and Foote, RH. 1982. J Anim Sci. 54: 1105-10. PMID: 7107529
- Lipid-based slow-release formulation of amikacin sulfate reduces foreign body-associated infections in mice. | Roehrborn, AA., et al. 1995. Antimicrob Agents Chemother. 39: 1752-5. PMID: 7486914
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Amikacin sulfate salt, 5 g | sc-239222 | 5 g | $369.00 |