Molecular structure of Amikacin disulfate, CAS Number: 39831-55-5
Amikacin disulfate (CAS 39831-55-5)
Application:
Amikacin disulfate is an aminoglycoside antibiotic that is active against gram-negative bacteria
CAS Number:
39831-55-5
Molecular Weight:
781.75
Molecular Formula:
C22H43N5O13•2H2SO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Amikacin disulfate, also known as BB-K 8, is an aminoglycoside antibiotic that is active against gram-negative bacteria. The activity of Amikacin is similar to that of Kanamycin (sc-29069) and Gentamicin (sc-29066). Amikacin has been used in different types of renal studies. We supply the Amikacin disulfate form. Amikacin Sulfate is a potent antibiotic derived from kanamycin with broad-spectrum activity. It belongs to the class of aminoglycosides and acts by binding irreversibly to the 30S ribosomal subunit in bacteria. Specifically, it interacts with the 16S rRNA and S12 protein within the subunit, disrupting translational initiation and causing mRNA misreading.
Amikacin disulfate (CAS 39831-55-5) References
- Immunosensor based on magnetic relaxation switch and biotin-streptavidin system for the detection of Kanamycin in milk. | Chen, YP., et al. 2013. Biosens Bioelectron. 39: 112-7. PMID: 22854330
- Urinary tract infections in patients with orthotopic neobladder. | Mano, R., et al. 2014. Urol Oncol. 32: 50.e9-14. PMID: 24239471
- Salmonella enterica subsp. enterica Serovar Heidelberg Food Isolates Associated with a Salmonellosis Outbreak Have Enhanced Stress Tolerance Capabilities. | Etter, AJ., et al. 2019. Appl Environ Microbiol. 85: PMID: 31175193
- Supplemental Antibiotics in a Commercial Extender for Stallion Semen. | Hernández-Avilés, C., et al. 2019. J Equine Vet Sci. 80: 33-35. PMID: 31443830
- Inclusion of supplemental antibiotics (amikacin - penicillin) in a commercial extender for stallion semen: Effects on sperm quality, bacterial growth, and fertility following cooled storage. | Hernández-Avilés, C., et al. 2020. Theriogenology. 158: 209-217. PMID: 32971438
- Imine bond formation as a tool for incorporation of amikacin in self-emulsifying drug delivery systems (SEDDS). | Dizdarević, A., et al. 2021. Eur J Pharm Biopharm. 162: 82-91. PMID: 33737147
- Comparative in vitro activity of three aminoglycosidic antibiotics: BB-K8, kanamycin, and gentamicin. | Yu, PK. and Washington, JA. 1973. Antimicrob Agents Chemother. 4: 133-9. PMID: 4208506
- Amikacin (BB-K8) treatment of multiple-drug resistant Proteus infections. | Sharp, PM., et al. 1974. Antimicrob Agents Chemother. 5: 435-8. PMID: 4462458
- Pharmacology of amikacin in humans. | Bodey, GP., et al. 1974. Antimicrob Agents Chemother. 5: 508-12. PMID: 4462465
- Pharmacokinetics of Amikacin (BB-K8) in patients with normal or impaired renal function. | Lanao, JM., et al. 1979. Int J Clin Pharmacol Biopharm. 17: 171-5. PMID: 447438
- BB-K 8, a new semisynthetic aminoglycoside antibiotic. | Kawaguchi, H., et al. 1972. J Antibiot (Tokyo). 25: 695-708. PMID: 4568692
- Comparative pharmacokinetics of BB-K8 and kanamycin in dogs and humans. | Cabana, BE. and Taggart, JG. 1973. Antimicrob Agents Chemother. 3: 478-83. PMID: 4790604
- Amikacin disulfate: an aminoglycoside antibiotic drug as a corrosion inhibitor for copper in 1 M nitric acid medium | G. Karthik & M. Sundaravadivelu. 2016. Journal of Adhesion Science and Technology. 30.
- Evaluation of inhibitive performance of Ibuprofen drug on copper in 0.5 M H2SO4 | I.G. Akande a, O.S.I. Fayomi b c, O.J. Adelakun b. 2020. Case Studies in Chemical and Environmental Engineering. 2.
- Rapid detection of kanamycin using cooperative recognition split aptamer and graphene oxide nanosheets | Hua Ye, Tianxiang Wan, Xinfu Li, Chao Li, Kuo He & Yuanxin Guo. 2023. Journal of Food Measurement and Characterization. 17: 2144–2151.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Amikacin disulfate, 250 mg | sc-202457 | 250 mg | $51.00 | |||
Amikacin disulfate, 1 g | sc-202457A | 1 g | $153.00 |