Molecular structure of Amidepsine D
Amidepsine D (CAS 79786-34-8)
Application:
Amidepsine D is an inhibitor of DGAT (diacylglycerol acyltransferase)
CAS Number:
79786-34-8
Molecular Weight:
496.5
Molecular Formula:
C26H24O10
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Amidepsine D has found extensive application in diverse scientific research endeavors. It has been employed to investigate the impact of small molecules on biological systems, specifically their influence on cell growth, differentiation, gene expression, and protein production. The prevailing hypothesis suggests that Amidepsine D exerts its effects by binding to a distinct receptor located on the cell surface. This binding event initiates a series of biochemical reactions that subsequently induce alterations in gene expression, protein production, and various other cellular processes.
Amidepsine D (CAS 79786-34-8) References
- Potential therapeutics for obesity and atherosclerosis: inhibitors of neutral lipid metabolism from microorganisms. | Tomoda, H. and Omura, S. 2007. Pharmacol Ther. 115: 375-89. PMID: 17614133
- Expression of two human acyl-CoA:diacylglycerol acyltransferase isozymes in yeast and selectivity of microbial inhibitors toward the isozymes. | Inokoshi, J., et al. 2009. J Antibiot (Tokyo). 62: 51-4. PMID: 19132064
- Development of a Fluorescent Probe for M2 Macrophages via Gating-Oriented Live-Cell Distinction. | Cho, H., et al. 2023. J Am Chem Soc. 145: 2951-2957. PMID: 36705574
- Amidepsines, inhibitors of diacylglycerol acyltransferase produced by Humicola sp. FO-2942. I. Production, isolation and biological properties. | Tomoda, H., et al. 1995. J Antibiot (Tokyo). 48: 937-41. PMID: 7592058
Inhibitor of:
DGAT.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Amidepsine D, 1 mg | sc-221245 | 1 mg | $272.00 | |||
Amidepsine D, 2.5 mg | sc-221245A | 2.5 mg | $554.00 |