Molecular structure of Ambuic acid, CAS Number: 340774-69-8
Ambuic acid (CAS 340774-69-8)
Alternate Names:
(+)-Ambuic acid
Application:
Ambuic acid is A chemical that inhibits the biosynthesis of cyclic peptide quormones
CAS Number:
340774-69-8
Molecular Weight:
350.41
Molecular Formula:
C16H26O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Ambuic acid is a compound that functions as an inhibitor of certain enzymes involved in specific cellular processes. It acts by binding to the active site of the enzyme, thereby preventing its normal function and disrupting the biochemical pathways in which it participates. This disruption ultimately leads to the inhibition of key cellular processes, affecting the growth and development of the target organism. Ambuic acid′s mechanism of action involves interfering with the catalytic activity of the enzyme, thereby impeding its ability to carry out its normal function within the cell. Its specific mechanism of action may be a useful compound for elucidating the biochemical pathways and molecular interactions involved in various biological systems.
Ambuic acid (CAS 340774-69-8) References
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- Stereochemical analysis by solid-state NMR: structural predictions in ambuic acid. | Harper, JK., et al. 2003. J Org Chem. 68: 4609-14. PMID: 12790563
- Characterizing challenging microcrystalline solids with solid-state NMR shift tensor and synchrotron X-ray powder diffraction data: structural analysis of ambuic acid. | Harper, JK., et al. 2006. J Am Chem Soc. 128: 1547-52. PMID: 16448125
- Ambuic acid inhibits the biosynthesis of cyclic peptide quormones in gram-positive bacteria. | Nakayama, J., et al. 2009. Antimicrob Agents Chemother. 53: 580-6. PMID: 19015326
- Microsporols A-C from the Plant Endophytic Fungus Pestalotiopsis microspore. | Wu, X., et al. 2015. Nat Prod Commun. 10: 1643-6. PMID: 26669093
- Hybrid Quadrupole-Orbitrap mass spectrometry for quantitative measurement of quorum sensing inhibition. | Todd, DA., et al. 2016. J Microbiol Methods. 127: 89-94. PMID: 27237773
- Anti-proliferative ambuic acid derivatives from Hawaiian endophytic fungus Pestalotiopsis sp. FT172. | Li, CS., et al. 2017. Phytochemistry. 140: 77-82. PMID: 28463686
- Signal Biosynthesis Inhibition with Ambuic Acid as a Strategy To Target Antibiotic-Resistant Infections. | Todd, DA., et al. 2017. Antimicrob Agents Chemother. 61: PMID: 28607020
- Anti-inflammatory action of ambuic acid, a natural product isolated from the solid culture of Pestalotiopsis neglecta, through blocking ERK/JNK mitogen-activated protein kinase signaling pathway. | Zhang, Q., et al. 2018. Exp Ther Med. 16: 1538-1546. PMID: 30116402
- Potential of MurA Enzyme and GBAP in Fsr Quorum Sensing System as Antibacterial Drugs Target: In vitro and In silico Study of Antibacterial Compounds from Myrmecodia pendans. | Apriyanti, E., et al. 2021. Comb Chem High Throughput Screen. 24: 109-118. PMID: 32598250
- Bio-Mechanism of Catechin as Pheromone Signal Inhibitor: Prediction of Antibacterial Agent Action Mode by In Vitro and In Silico Study. | Kurnia, D., et al. 2021. Molecules. 26: PMID: 34770790
- Two ambuic acid dimers derived from homo-endo Diels-Alder reaction from Pestalotiopsis versicolor. | Li, DY., et al. 2022. J Asian Nat Prod Res. 1-9. PMID: 36264599
- The Potential of 24-Propylcholestrol as Antibacterial Oral Bacteria of Enterococcus faecalis ATCC 29212 and Inhibitor Biofilms Formation: in vitro and in silico Study. | Windaryanti, D., et al. 2022. Adv Appl Bioinform Chem. 15: 99-111. PMID: 36578792
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ambuic acid, 250 µg | sc-396545 | 250 µg | $84.00 |