Molecular structure of Alverine Citrate, CAS Number: 5560-59-8
Alverine Citrate (CAS 5560-59-8)
Alternate Names:
N-Ethyl-3,3′-diphenyldipropylamine; NSC 35459
Application:
Alverine Citrate is an β3-AR (adrenergic-β3 receptor) agonist and an inhibitor of SR-1A.
CAS Number:
5560-59-8
Molecular Weight:
473.56
Molecular Formula:
C26H35NO7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Alverine Citrate is an antispasmodic, and an adrenergic-β3 receptor agonist.
Alverine Citrate (CAS 5560-59-8) References
- Effects of alverine citrate on cat intestinal mechanoreceptor responses to chemical and mechanical stimuli. | Abysique, A., et al. 1999. Aliment Pharmacol Ther. 13: 561-6. PMID: 10215743
- Rectal antinociceptive properties of alverine citrate are linked to antagonism at the 5-HT1A receptor subtype. | Coelho, AM., et al. 2001. J Pharm Pharmacol. 53: 1419-26. PMID: 11697552
- Chemogenomic profiling: identifying the functional interactions of small molecules in yeast. | Giaever, G., et al. 2004. Proc Natl Acad Sci U S A. 101: 793-8. PMID: 14718668
- Alverine citrate induced acute hepatitis. | Arhan, M., et al. 2004. World J Gastroenterol. 10: 2303-4. PMID: 15259090
- Evolving mechanisms of action of alverine citrate on phasic smooth muscles. | Hayase, M., et al. 2007. Br J Pharmacol. 152: 1228-38. PMID: 17934514
- Dyclonine and alverine citrate enhance the cytotoxic effects of proteasome inhibitor MG132 on breast cancer cells. | Ju, D., et al. 2009. Int J Mol Med. 23: 205-9. PMID: 19148544
- Alverine citrate, simeticone, and Rome III irritable bowel syndrome. | Ford, AC. 2010. Aliment Pharmacol Ther. 31: 767-8; author reply 768-9. PMID: 20415841
- Influence of simethicone and alverine on stress-induced alterations of colonic permeability and sensitivity in rats: beneficial effect of their association. | Bueno, L., et al. 2013. J Pharm Pharmacol. 65: 567-73. PMID: 23488786
- Identification of alverine and benfluorex as HNF4α activators. | Lee, SH., et al. 2013. ACS Chem Biol. 8: 1730-6. PMID: 23675775
- Role of antispasmodics in the treatment of irritable bowel syndrome. | Annaházi, A., et al. 2014. World J Gastroenterol. 20: 6031-43. PMID: 24876726
- Anxiolytic-like effects of alverine citrate in experimental mouse models of anxiety. | Gupta, D., et al. 2014. Eur J Pharmacol. 742: 94-101. PMID: 25199966
- Alverine citrate promotes myogenic differentiation and ameliorates muscle atrophy. | Yoon, JH., et al. 2022. Biochem Biophys Res Commun. 586: 157-162. PMID: 34847441
- The 5-HT and PLC Signaling Pathways Regulate the Secretion of IL-1β, TNF-α and BDNF from NG2 Cells. | Yang, T., et al. 2022. Evid Based Complement Alternat Med. 2022: 7425538. PMID: 35600957
- Qualitative and quantitative tests for alverine citrate. | Salim, EF. and Ebert, WR. 1967. J Pharm Sci. 56: 1162-3. PMID: 6049704
Inhibitor of:
SR-1A.Activator of:
beta3-AR.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Alverine Citrate, 5 g | sc-210792 | 5 g | $300.00 |