Date published: 2025-9-30

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Altrenogest (CAS 850-52-2)

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Alternate Names:
Regumate
Application:
Altrenogest is a synthetic trienic C21 steroidal progestomimetic
CAS Number:
850-52-2
Molecular Weight:
310.43
Molecular Formula:
C21H26O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Altrenogest is a synthetic progestin that functions as a progestational agent. It acts by binding to progesterone receptors in the reproductive tract, exerting its effects on the endometrium and myometrium. Altrenogest′s mechanism of action involves altering the hormonal environment, leading to changes in the uterine lining and inhibiting follicular development. Altrenogest also suppresses the secretion of gonadotropins, thereby preventing ovulation. At the molecular level, it modulates gene expression and protein synthesis, influencing the menstrual cycle and reproductive processes. Altrenogest′s function in experimental applications involves studying its impact on the female reproductive system and its potential applications in manipulating estrous cycles in animals.


Altrenogest (CAS 850-52-2) References

  1. Altrenogest treatment during late pregnancy did not reduce colostrum yield in primiparous sows.  |  Foisnet, A., et al. 2010. J Anim Sci. 88: 1684-93. PMID: 20118420
  2. Effects of altrenogest on reproductive performance of gilts and sows: A meta-analysis.  |  Wang, Z., et al. 2018. Anim Reprod Sci. 197: 10-21. PMID: 30197055
  3. Pharmacokinetics of Intrarectal Altrenogest in Horses.  |  Ellis, KE., et al. 2019. J Equine Vet Sci. 72: 41-46. PMID: 30929782
  4. Pharmacokinetics of altrenogest in gilts.  |  Xiao, H., et al. 2019. J Vet Pharmacol Ther. 42: 660-664. PMID: 31222770
  5. Investigations on residual elimination of altrenogest oral solution in pigs and the withdrawal time.  |  Li, Y., et al. 2021. Anim Biotechnol. 32: 310-317. PMID: 31814507
  6. Altrenogest affects the development and endocrine milieu of ovarian follicles in prepubertal and mature gilts†.  |  Ziecik, AJ., et al. 2020. Biol Reprod. 103: 1069-1084. PMID: 32744329
  7. Unravelling androgens in sport: Altrenogest shows strong activation of the androgen receptor in a mammalian cell bioassay.  |  Gillon, A., et al. 2021. Drug Test Anal. 13: 523-528. PMID: 33037724
  8. Downregulation of testicular function in the goat by altrenogest.  |  Mihsler-Kirsch, L., et al. 2021. BMC Vet Res. 17: 183. PMID: 33947415
  9. A Short-Term Altrenogest Treatment Post-weaning Followed by Superovulation Reduces Pregnancy Rates and Embryo Production Efficiency in Multiparous Sows.  |  Gonzalez-Ramiro, H., et al. 2021. Front Vet Sci. 8: 771573. PMID: 34869743
  10. Control of parturition in hyperprolific sows by using altrenogest and double administrations of PGF2α.  |  Taechamaeteekul, P., et al. 2022. Theriogenology. 181: 24-33. PMID: 35063918
  11. Altrenogest treatment reduces the stress response of three-year-old warmblood mares during their initial equestrian training.  |  Kaps, M., et al. 2022. Domest Anim Endocrinol. 80: 106728. PMID: 35421809
  12. Altrenogest Supplementation during Early Pregnancy Improves Reproductive Outcome in Pigs.  |  Muro, BBD., et al. 2022. Animals (Basel). 12: PMID: 35883348
  13. Administration of Altrenogest to Maintain Pregnancy in Asian Elephants (Elephas maximus).  |  Kottwitz, JJ., et al. 2022. Animals (Basel). 12: PMID: 35883398

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Altrenogest, 100 mg

sc-233848
100 mg
$102.00

Altrenogest, 250 mg

sc-233848A
250 mg
$242.00

Altrenogest, 1 g

sc-233848B
1 g
$604.00

Altrenogest, 5 g

sc-233848C
5 g
$2448.00

Altrenogest, 10 g

sc-233848D
10 g
$4641.00