Molecular structure of Altersolanol A, CAS Number: 22268-16-2
Altersolanol A (CAS 22268-16-2)
Alternate Names:
As-A 2; (1R-(1α,2β,3β,4α))-1,2,3,4-Tetrahydro-1,2,3,4,5-pentahydroxy-7-methoxy-2-methyl-9,10-anthracenedione
Application:
Altersolanol A is a tetrahydroanthraquinone with phytotoxic and antibacterial activity
CAS Number:
22268-16-2
Purity:
≥97%
Molecular Weight:
336.29
Molecular Formula:
C16H16O8
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Altersolanol A is a tetrahydroanthraquinone with phytotoxic and antibacterial activity. Altersolanol A, a sesquiterpenoid compound naturally found in the leaves and twigs of the Altersolanol tree (Eucalyptus alba), exhibits remarkable biological activities. While the precise mechanism of action of Altersolanol A remains incompletely understood, current understanding suggests that it operates by inhibiting the production of pro-inflammatory cytokines and modulating the activity of specific enzymes involved in inflammation. Furthermore, its antioxidant activity is attributed to its capacity to scavenge free radicals.
Altersolanol A (CAS 22268-16-2) References
- Biologically active polyketide metabolites from an undetermined fungicolous hyphomycete resembling Cladosporium. | Höller, U., et al. 2002. J Nat Prod. 65: 876-82. PMID: 12088431
- Natural occurrence of fungi and fungal metabolites in moldy tomatoes. | Andersen, B. and Frisvad, JC. 2004. J Agric Food Chem. 52: 7507-13. PMID: 15675796
- Secondary metabolite profiling of Alternaria dauci, A. porri, A. solani, and A. tomatophila. | Andersen, B., et al. 2008. Mycol Res. 112: 241-50. PMID: 18262401
- Absolute stereochemistry of altersolanol A and alterporriols. | Kanamaru, S., et al. 2012. Chirality. 24: 137-46. PMID: 22180221
- Anticancer effect of altersolanol A, a metabolite produced by the endophytic fungus Stemphylium globuliferum, mediated by its pro-apoptotic and anti-invasive potential via the inhibition of NF-κB activity. | Teiten, MH., et al. 2013. Bioorg Med Chem. 21: 3850-8. PMID: 23664494
- Xylanthraquinone, a new anthraquinone from the fungus Xylaria sp. 2508 from the South China Sea. | Huang, X., et al. 2014. Nat Prod Res. 28: 111-4. PMID: 24205843
- Altersolanol A: a selective cytotoxic anthraquinone from a Phomopsis sp. | Mishra, PD., et al. 2015. Lett Appl Microbiol. 60: 387-91. PMID: 25534717
- Screening of endophytic fungi with anti-phytopathogen activities from Heptacodium miconioides. | Wang, L., et al. 2015. Wei Sheng Wu Xue Bao. 55: 33-9. PMID: 25958680
- First enantioselective total synthesis of altersolanol A. | Mechsner, B., et al. 2018. Org Biomol Chem. 16: 7674-7681. PMID: 30283967
- Enantioselective total synthesis of altersolanol A and N. | Mechsner, B., et al. 2019. Bioorg Med Chem. 27: 2991-2997. PMID: 31072649
- High-performance liquid chromatographic determination of macrosporin, altersolanol A, alterporriol A, B and C in fermentation of Alternaria porri (Ellis) Ciferri. | Suemitsu, R., et al. 1988. J Chromatogr. 454: 406-10. PMID: 3235604
- Recent Advances in Alternaria Phytotoxins: A Review of Their Occurrence, Structure, Bioactivity, and Biosynthesis. | Wang, H., et al. 2022. J Fungi (Basel). 8: PMID: 35205922
- Mycoviral gene integration converts a plant pathogenic fungus into a biocontrol agent. | Liu, H., et al. 2022. Proc Natl Acad Sci U S A. 119: e2214096119. PMID: 36469771
- Metabolites of Dactylaria lutea. The structures of dactylariol and the antiprotozoal antibiotic dactylarin. | Becker, AM., et al. 1978. J Antibiot (Tokyo). 31: 324-9. PMID: 566263
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Altersolanol A, 1 mg | sc-202455 | 1 mg | $242.00 |