Molecular structure of Alpinetin
Alpinetin (CAS 36052-37-6)
Alternate Names:
(S)-7-Hydroxy-5-methoxyflavanone
CAS Number:
36052-37-6
Molecular Weight:
270.28
Molecular Formula:
C16H14O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Alpinetin, a flavonoid compound, is tested its antioxidant properties and its potential to influence cellular health. Scientists apply it in molecular biology and biochemistry to understand the intricacies of cellular responses and the regulation of proteins. Alpinetin works with certain enzymes that are associated with the body′s response and its ability to neutralize free radicals, thereby protecting cells from oxidative harm. Additionally, the compound is used in materials science to explore its effects on the stability and functionality of biomaterials.
Alpinetin (CAS 36052-37-6) References
- Alpinetin inhibits lipopolysaccharide-induced acute kidney injury in mice. | Huang, Y., et al. 2015. Int Immunopharmacol. 28: 1003-8. PMID: 26321118
- Alpinetin exerts anti-colitis efficacy by activating AhR, regulating miR-302/DNMT-1/CREB signals, and therefore promoting Treg differentiation. | Lv, Q., et al. 2018. Cell Death Dis. 9: 890. PMID: 30166541
- Alpinetin improves intestinal barrier homeostasis via regulating AhR/suv39h1/TSC2/mTORC1/autophagy pathway. | Miao, Y., et al. 2019. Toxicol Appl Pharmacol. 384: 114772. PMID: 31676321
- Alpinetin inhibits breast cancer growth by ROS/NF-κB/HIF-1α axis. | Zhang, T., et al. 2020. J Cell Mol Med. 24: 8430-8440. PMID: 32562470
- Alpinetin delays high-fat diet-aggravated lung carcinogenesis. | Hou, S., et al. 2021. Basic Clin Pharmacol Toxicol. 128: 410-418. PMID: 33259132
- Alpinetin protects against hepatic ischemia/reperfusion injury in mice by inhibiting the NF-κB/MAPK signaling pathways. | Pan, J., et al. 2021. Int Immunopharmacol. 95: 107527. PMID: 33743314
- Alpinetin exerts anti-inflammatory, anti-oxidative and anti-angiogenic effects through activating the Nrf2 pathway and inhibiting NLRP3 pathway in carbon tetrachloride-induced liver fibrosis. | Zhu, Z., et al. 2021. Int Immunopharmacol. 96: 107660. PMID: 33862553
- Alpinetin Attenuates Persistent Inflammation, Immune Suppression, and Catabolism Syndrome in a Septic Mouse Model. | Liu, Y., et al. 2021. J Immunol Res. 2021: 9998517. PMID: 34285925
- Alpinetin: A Review of Its Pharmacology and Pharmacokinetics. | Zhao, G., et al. 2022. Front Pharmacol. 13: 814370. PMID: 35185569
- Alpinetin inhibits macrophage infiltration and atherosclerosis by improving the thiol redox state: Requirement of GSk3β/Fyn-dependent Nrf2 activation. | Dong, D., et al. 2022. FASEB J. 36: e22261. PMID: 35332570
- Alpinetin: a Dietary Flavonoid with Diverse Anticancer Effects. | Gul, S., et al. 2022. Appl Biochem Biotechnol. 194: 4220-4243. PMID: 35567708
- Alpinetin promotes hair regeneration via activating hair follicle stem cells. | Fan, X., et al. 2022. Chin Med. 17: 63. PMID: 35637486
- Alpinetin ameliorates bone loss in LPS-induced inflammation osteolysis via ROS mediated P38/PI3K signaling pathway. | Wei, L., et al. 2022. Pharmacol Res. 184: 106400. PMID: 35988868
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Alpinetin, 10 mg | sc-460591 | 10 mg | $392.00 |