alpha-Zearalenol CAS: 36455-72-8
MF: C18H24O5
MW: 320.3
An estrogenic synthetic derivative of the Zeralenone mycotoxin.

α-Zearalenol (CAS 36455-72-8)

α-Zearalenol | CAS 36455-72-8 is rated 4.0 out of 5 by 1.
  • y_2021, m_11, d_26, h_18
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.20
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_202388, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 110ms
  • REVIEWS, PRODUCT
loading
5
0
4
1
3
0
2
0
1
0
Application: α-Zearalenol is an estrogenic synthetic derivative of the Zeralenone mycotoxin
CAS Number: 36455-72-8
Purity: >99%
Molecular Weight: 320.3
Molecular Formula: C18H24O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits
loading

α-Zearalenol is a synthetic derivative of the macrolactone mycotoxin zearalenone (sc-204943) isolated from the Fusarium roseum fungus. α-Zearalenol is estrogenically active and demonstrates induction of premature uterine growth, increase of nuclear estrogen receptor levels, and a five fold increase of ornithine decarboxylase level (ODC). The increase of ODC level was 20-fold more pronounced with α-zearalenol than zearalenone, and α-Zearalenol demonstrated three times more potent estrogenic activity than zearalenone.


References

1. Hagler, W.M., et al. 1979. Appl. Environ. Microbiol. 37: 849-853. PMID: 485136
2. Mirocha, C.J., et al. 1979. Appl. Environ. Microbiol. 38: 749-750. PMID: 161492
3. Powell-Jones, W., et al. 1981. Mol. Pharmacol. 20: 35-42. PMID: 6457245
4. Sheehan, D.M., et al. 1984. Teratology. 29: 383-392. PMID: 6235618
5. Luongo, D., et al. 2008. Toxicon. 52: 156-162. PMID: 18620720

Physical State :
Solid
Derived From :
Fusarium
Solubility :
Soluble in water (partly), ethanol, methanol, DMF, and DMSO.
Storage :
Store at -20° C
Melting Point :
158-166° C
Boiling Point :
598.97° C at 760 mmHg (Predicted)
Density :
1.17 g/cm3 (Predicted)
Refractive Index :
n20D 1.55 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
MDL Number :
MFCD16657008
SMILES :
C[[email protected]]1CCC[[email protected]@H](CCC/C=C/C2=CC(=CC(=C2C(=O)O1)O)O)O

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

alpha-Zearalenol (CAS 36455-72-8)  Product Citations

See how others have used alpha-Zearalenol (CAS 36455-72-8). Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 26255852  Nakamura, U. et al. 2015. Theriogenology. 84: 1342-9.

Citations 1 to 1 of 1 total
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 98ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Rated 4 out of 5 by from I will rate this product a 4 and rate 5 I will rate this product a 4 and rate 5 for your logistics, customer service and support.
Date published: 2015-04-20
  • y_2021, m_11, d_26, h_18
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.20
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_202388, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 13ms
  • REVIEWS, PRODUCT