Date published: 2025-12-11

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(−)-α-Santonin (CAS 481-06-1)

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Alternate Names:
(3S,5aS,9bS)-3a,5,5a,9b-Tetrahydro-3,5a,9-trimethylnaphtho[1,2-b]furan-2,8(3H,4H)dione
CAS Number:
481-06-1
Purity:
≥98%
Molecular Weight:
246.30
Molecular Formula:
C15H18O3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(−)-α-Santonin is a compound that functions as a potent anthelmintic agent, targeting parasitic worms. Its mechanism of action involves disrupting the nervous system of the parasites, leading to paralysis and subsequent expulsion from the host organism. (−)-Å-Santonin exerts its effects by binding to and activating specific receptors in the parasites, ultimately causing neuromuscular blockade. This mechanism interferes with the parasites′ ability to maintain normal muscle function, leading to their immobilization and eventual elimination from the host. (−)-α-Santonin′s activity at the molecular level involves modulation of neurotransmitter release and inhibition of neuromuscular transmission in the targeted parasites. (−)-Å-Santonin′s specific interactions with the nervous system of the parasites make it useful for studying the molecular mechanisms underlying anthelmintic activity.


(−)-α-Santonin (CAS 481-06-1) References

  1. Synthesis of phytuberin. 4-endo-tet acid-catalyzed cyclization of alpha-hydroxy epoxides.  |  Prangé, T., et al. 2003. J Org Chem. 68: 4422-31. PMID: 12762747
  2. Growth, terpenoid production and antibacterial activity of an in vitro culture of the liverwort Fossombronia pusilla.  |  Sauerwein, M. and Becker, H. 1990. Planta Med. 56: 364-7. PMID: 2236288

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(−)-α-Santonin, 5 g

sc-252339
5 g
$106.00