Molecular structure of α-NETA, CAS Number: 31059-54-8
α-NETA (CAS 31059-54-8)
See product citations (3)
Alternate Names:
2-naphthoylethyltrimethylammonium
Application:
α-NETA is a fluorescent choactase inhibitor
CAS Number:
31059-54-8
Purity:
≥97%
Molecular Weight:
369.24
Molecular Formula:
C16H20INO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
α-NETA, also known as 2-Naphthoylethyltrimethylammonium (2-N-Et-TMA), is a soluble organic compound that belongs to the group of quaternary ammonium salts, containing a nitrogen atom with four alkyl groups attached. Its specific structure allows it to interact with proteins and cellular components in a targeted manner through electrostatic interactions, leading to changes in their structure and function. Furthermore, the compound is able to affect lipid membranes by increasing their permeability.
α-NETA (CAS 31059-54-8) References
- A novel CMKLR1 small molecule antagonist suppresses CNS autoimmune inflammatory disease. | Graham, KL., et al. 2014. PLoS One. 9: e112925. PMID: 25437209
- TAAR5 receptor agonist affects sensory gating in rats. | Aleksandrov, AA., et al. 2018. Neurosci Lett. 666: 144-147. PMID: 29288046
- Role of chemerin/CMKLR1 in the maintenance of early pregnancy. | Yang, X., et al. 2018. Front Med. 12: 525-532. PMID: 29556954
- Novel CMKLR1 Inhibitors for Application in Demyelinating Disease. | Kumar, V., et al. 2019. Sci Rep. 9: 7178. PMID: 31073181
- Putative Trace-Amine Associated Receptor 5 (TAAR5) Agonist α-NETA Increases Electrocorticogram Gamma-Rhythm in Freely Moving Rats. | Belov, DR., et al. 2020. Cell Mol Neurobiol. 40: 203-213. PMID: 31385135
- Effect of alpha-NETA on auditory event related potentials in sensory gating study paradigm in mice. | Aleksandrov, AA., et al. 2019. Neurosci Lett. 712: 134470. PMID: 31476355
- α-NETA induces pyroptosis of epithelial ovarian cancer cells through the GSDMD/caspase-4 pathway. | Qiao, L., et al. 2019. FASEB J. 33: 12760-12767. PMID: 31480859
- Putative TAAR5 agonist alpha-NETA affects event-related potentials in oddball paradigm in awake mice. | Aleksandrov, AA., et al. 2020. Brain Res Bull. 158: 116-121. PMID: 32151716
- 2-(alpha-Naphthoyl)ethyltrimethylammonium iodide and its beta-isomer: new selective, stable and fluorescent inhibitors of choline acetyltransferase. | Sastry, BV., et al. 1988. J Pharmacol Exp Ther. 245: 72-80. PMID: 3361452
- Chemerin promotes the pathogenesis of preeclampsia by activating CMKLR1/p-Akt/CEBPɑ axis and inducing M1 macrophage polarization. | Ji, ZS., et al. 2022. Cell Biol Toxicol. 38: 611-628. PMID: 34398343
- The Regulatory Roles of Chemerin-Chemokine-Like Receptor 1 Axis in Placental Development and Vascular Remodeling During Early Pregnancy. | Zhang, Q., et al. 2022. Front Cell Dev Biol. 10: 883636. PMID: 35656551
- Alpha-NETA, as a CMKLR1 Small Molecule Antagonist, Protects against Renal Ischemia Reperfusion Injury in Mice. | Peng, X., et al. 2022. Protein Pept Lett. 29: 962-970. PMID: 35996267
- Chemerin-9 in paraventricular nucleus increases sympathetic outflow and blood pressure via glutamate receptor-mediated ROS generation. | Wang, JX., et al. 2022. Eur J Pharmacol. 936: 175343. PMID: 36306926
- Targeting the chemerin/CMKLR1 axis by small molecule antagonist α-NETA mitigates endometriosis progression. | Yu, M., et al. 2022. Front Pharmacol. 13: 985618. PMID: 36523492
Inhibitor of:
Choactase.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
α-NETA, 5 mg | sc-221190 | 5 mg | $61.00 | |||
α-NETA, 25 mg | sc-221190A | 25 mg | $164.00 | |||
α-NETA, 50 mg | sc-221190B | 50 mg | $261.00 | |||
α-NETA, 100 mg | sc-221190C | 100 mg | $440.00 |