Molecular structure of α-Naphthyl Acid Phosphate Monosodium Salt, CAS Number: 81012-89-7
α-Naphthyl Acid Phosphate Monosodium Salt (CAS 81012-89-7)
Alternate Names:
α-Naphthyl phosphoric acid, monosodium salt
Application:
α-Naphthyl Acid Phosphate Monosodium Salt is a non-specific phosphatase inhibitor
CAS Number:
81012-89-7
Purity:
99%
Molecular Weight:
246.13
Molecular Formula:
C10H8O4PNa
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
alpha-Naphthyl Acid Phosphate, Monosodium Salt, a product of kinase-mediated phosphorylation of 1-naphthol in the cell, is recognized as an alkaline, acid, and protein phosphatase inhibitor. This compound has also been shown to dephosphorylate the actin-depolymerizing protein, Cofilin 1, in platelets. Other studies suggest that alpha-Naphthyl Acid Phosphate may decrease Ca2+-induced secretion in streptolysic O (SLO)-permeabilized chief cells from guinea pig stomach.
α-Naphthyl Acid Phosphate Monosodium Salt (CAS 81012-89-7) References
- Changes in the metaphase transit times and the pattern of sister chromatid separation in stamen hair cells of Tradescantia after treatment with protein phosphatase inhibitors. | Wolniak, SM. and Larsen, PM. 1992. J Cell Sci. 102 (Pt 4): 691-715. PMID: 1331129
- Pharmacological manipulation of the akt signaling pathway regulates myxoma virus replication and tropism in human cancer cells. | Werden, SJ. and McFadden, G. 2010. J Virol. 84: 3287-302. PMID: 20106927
- Dephosphorylation of cofilin in stimulated platelets: roles for a GTP-binding protein and Ca2+. | Davidson, MM. and Haslam, RJ. 1994. Biochem J. 301 (Pt 1): 41-7. PMID: 8037689
- Regulation of calcium-induced exocytosis from gastric chief cells by protein phosphatase-2B (calcineurin). | Raufman, JP., et al. 1997. Biochim Biophys Acta. 1357: 73-80. PMID: 9202177
- Mitotic disturbance by carbaryl and the metabolite 1-naphthol may involve kinase-mediated phosphorylation of 1-naphthol to the protein phosphatase inhibitor 1-naphthylphosphate. | Renglin, A., et al. 1998. Mutagenesis. 13: 345-52. PMID: 9717170
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
α-Naphthyl Acid Phosphate Monosodium Salt, 5 g | sc-202898 | 5 g | $69.00 |