α-Naphthoflavone is a naturally occurring compound found in Passiflora. α-Naphthoflavone is an aryl hydrocarbon receptor antagonist and inhibitor of CYP1A1 gene expression. Experiments show inhibitory properties towards cytochrome P450 enzymes, CYP1A1 (P4501A1) and CYP1A2 (P4501A2) (competetive binding) with stimulatory activities towards CYP3A4 (P4503A4) (selective binding). α-Naphthoflavone is an inhibitor of CYP19.
1. Dhawan, K., et al. 2004. J Ethnopharmacol. 94: 1-23. PMID: 15261959
See how others have used α-Naphthoflavone (CAS 604-59-1). Click on the entry to view the PubMed entry .
PMID: # 28949811 Quinney, SK. et al. 2017. Fetal Pediatr Pathol. 36: 400-411.
PMID: # 26752525 Raggi, F. et al. 2016. PloS one. 11: e0146729.
PMID: # 15261959 Dhawan, K. et al. 2004. J Ethnopharmacol. 94: 1-23.
Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2020 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.