α-Methyl-L-tryptophan (CAS 16709-25-4)
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α-Methyl-L-tryptophan is a compound that functions as a competitive inhibitor of the enzyme indoleamine 2,3-dioxygenase (IDO). It acts by binding to the active site of IDO, preventing the conversion of tryptophan to kynurenine. This inhibition of IDO activity leads to an accumulation of tryptophan and a decrease in the production of kynurenine and its downstream metabolites. In a research and development applications, α-Methyl-L-tryptophan may be used to study the role of IDO in immune regulation, inflammation, and cancer progression. By modulating the tryptophan-kynurenine pathway, α-Methyl-L-tryptophan allows the investigation of IDO inhibition on immune responses and disease pathogenesis at the molecular level. α-Methyl-L-tryptophan may be useful for understanding the molecular mechanisms underlying immune tolerance and disease progression in experimental models.
α-Methyl-L-tryptophan (CAS 16709-25-4) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
α-Methyl-L-tryptophan, 10 mg | sc-208508 | 10 mg | $460.00 | |||
α-Methyl-L-tryptophan, 100 mg | sc-208508A | 100 mg | $2800.00 |