Date published: 2025-10-14

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α-Methyl-D,L-tyrosine (CAS 620-30-4)

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Application:
α-Methyl-D,L-tyrosine is an antihypertensive tyrosine hydroxylase inhibitor
CAS Number:
620-30-4
Molecular Weight:
195.22
Molecular Formula:
C10H13NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Alpha-Methyl-D,L-tyrosine is a structural analog of the amino acid tyrosine. Alpha-Methyl-D,L-tyrosine has been studied for its ability to influence tyrosine metabolism and the biosynthesis of tyrosine-derived molecules. Tyrosine is a precursor for several important biochemical compounds, including neurotransmitters like dopamine and norepinephrine, as well as hormones such as thyroid hormones. By modulating the availability of tyrosine or interfering with its metabolic pathways, alpha-Methyl-D,L-tyrosine can be used to explore the physiological and pathological roles of these tyrosine-derived molecules. Furthermore, the study of alpha-Methyl-D,L-tyrosine and its effects on biochemical systems can provide insights into the mechanisms of enzyme inhibition, especially those involved in the hydroxylation of tyrosine, a critical step in the biosynthesis of several important biologically active compounds. Researchers can utilize this compound to investigate the complexities of metabolic regulation, neurotransmitter synthesis, and the balance of biochemical pathways that are essential for maintaining cellular function and overall organismal health.


α-Methyl-D,L-tyrosine (CAS 620-30-4) References

  1. Hydrogen peroxide degradation and selective carbidopa-induced cytotoxicity against human tumor lines.  |  Gilbert, JA., et al. 2005. Biochem Pharmacol. 69: 1159-66. PMID: 15794936
  2. Effects of intracellular administration of L-tyrosine and L-phenylalanine on voltage-operated calcium conductance in PC12 pheochromocytoma cells.  |  Kostyuk, PG., et al. 1991. Brain Res. 550: 11-4. PMID: 1653634
  3. [Effect of intracellular administration of L-tyrosine and L-phenylalanine on voltage dependent calcium current in PC 12 pheochromocytoma cells].  |  Martyniuk, AE. and Pogorelaia, NKh. 1991. Neirofiziologiia. 23: 105-11. PMID: 1674591
  4. Establishment and characterization of mammalian cell lines stably expressing human L-type amino acid transporters.  |  Morimoto, E., et al. 2008. J Pharmacol Sci. 108: 505-16. PMID: 19075510

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

α-Methyl-D,L-tyrosine, 2.5 g

sc-207231
2.5 g
$190.00