Molecular structure of α-Lactose monohydrate, CAS Number: 5989-81-1
α-Lactose monohydrate (CAS 5989-81-1)
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Alternate Names:
Milk sugar; 4-O-β-D-Galactopyranosyl-α-D-glucose
CAS Number:
5989-81-1
Purity:
≥97%
Molecular Weight:
360.31
Molecular Formula:
C12H22O11•H2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
α-Lactose monohydrate is a disaccharide sugar that is found in milk and other dairy products. It serves as a substrate for enzyme production, an energy source for bacterial growth, and a carbon source for biochemical reactions. It is also in the study of biochemical pathways. It acts as an osmotic agent and can be used to synthesize certain hormones and enzymes. The mechanism of action of α-Lactose monohydrate is based on the ability of the enzyme β-galactosidase to break down the lactose molecule into its component monosaccharides, glucose and galactose.
α-Lactose monohydrate (CAS 5989-81-1) References
- Assessing the re-crystallization behaviour of amorphous lactose using the RH-perfusion cell. | Timmermann, IL., et al. 2006. Eur J Pharm Biopharm. 64: 107-14. PMID: 16527465
- Quantitative X-ray diffraction determination of alpha-lactose monohydrate and beta-lactose in chocolate. | Thomas, NR., et al. 2009. J Food Sci. 74: C513-8. PMID: 19895454
- Spherical agglomerates of lactose with enhanced mechanical properties. | Lamešić, D., et al. 2017. Int J Pharm. 516: 247-257. PMID: 27866980
- Milling induced amorphisation and recrystallization of α-lactose monohydrate. | Badal Tejedor, M., et al. 2018. Int J Pharm. 537: 140-147. PMID: 29262302
- Imagine the Superiority of Dry Powder Inhalers from Carrier Engineering. | Mehta, P. 2018. J Drug Deliv. 2018: 5635010. PMID: 29568652
- A comparative study of the influence of alpha-lactose monohydrate particle morphology on granule and tablet properties after roll compaction/dry granulation. | Grote, S. and Kleinebudde, P. 2019. Pharm Dev Technol. 24: 314-322. PMID: 29757067
- Modification of α-lactose monohydrate as a direct compression excipient using roller compaction. | Abu Fara, D., et al. 2018. Drug Dev Ind Pharm. 44: 2038-2047. PMID: 30095020
- Conversion of α-lactose monohydrate to anhydrous form with superior tabletability by twin-screw extrusion at elevated temperature. | Batra, A., et al. 2020. Int J Pharm. 588: 119790. PMID: 32822779
- Stability of α-lactose monohydrate: The discovery of dehydration triggered solid-state epimerization. | Alzoubi, T., et al. 2021. Int J Pharm. 604: 120715. PMID: 34048927
- Terahertz Spectroscopic Analysis of Lactose in Infant Formula: Implications for Detection and Quantification. | Datta, S., et al. 2022. Molecules. 27: PMID: 35956992
- Crystallization Thermodynamics of α-Lactose Monohydrate in Different Solvents. | Guan, Y., et al. 2022. Pharmaceutics. 14: PMID: 36145520
- The Optimisation of Carrier Selection in Dry Powder Inhaler Formulation and the Role of Surface Energetics. | Abiona, O., et al. 2022. Biomedicines. 10: PMID: 36359226
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
α-Lactose monohydrate, 10 mg | sc-221188 | 10 mg | $36.00 | |||
α-Lactose monohydrate, 1 kg | sc-221188A | 1 kg | $126.00 |