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α-Ketoglutaric acid sodium salt (CAS 22202-68-2)

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Alternate Names:
2-oxoglutarate monobasic
CAS Number:
22202-68-2
Purity:
≥98%
Molecular Weight:
168.08
Molecular Formula:
C5H5NaO5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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α-Ketoglutaric acid sodium salt is a compound that functions as an intermediate in the tricarboxylic acid cycle. It plays a role in the metabolism of amino acids and is involved in the production of energy within cells. At the molecular level, it participates in the conversion of isocitrate to succinyl-CoA, a step in the cycle. Å-Ketoglutaric Acid Sodium Salt acts as a co-substrate for enzymes involved in the transfer of high-energy phosphate groups. Its mechanism of action involves facilitating the transfer of chemical groups between molecules, contributing to the energy production process. It is involved in the regulation of cellular redox balance and the synthesis of certain amino acids. α-Ketoglutaric acid sodium salt plays a significant functional role in cellular metabolism and energy production within experimental applications.


α-Ketoglutaric acid sodium salt (CAS 22202-68-2) References

  1. Development of amperometric α-ketoglutarate biosensor based on ruthenium-rhodium modified carbon fiber enzyme microelectrode.  |  Poorahong, S., et al. 2011. Biosens Bioelectron. 26: 3670-3. PMID: 21334188
  2. Multienzyme-modified biosensing surface for the electrochemical analysis of aspartate transaminase and alanine transaminase in human plasma.  |  Han, YD., et al. 2011. Anal Bioanal Chem. 400: 797-805. PMID: 21359826
  3. Nine post-translational modifications during the biosynthesis of cinnamycin.  |  Ökesli, A., et al. 2011. J Am Chem Soc. 133: 13753-60. PMID: 21770392
  4. Electrophysiological characterization of human and mouse sodium-dependent citrate transporters (NaCT/SLC13A5) reveal species differences with respect to substrate sensitivity and cation dependence.  |  Zwart, R., et al. 2015. J Pharmacol Exp Ther. 355: 247-54. PMID: 26324167
  5. A Micro-Platinum Wire Biosensor for Fast and Selective Detection of Alanine Aminotransferase.  |  Thuy, TN. and Tseng, TT. 2016. Sensors (Basel). 16: PMID: 27240366
  6. Identification of Ligand-Receptor Interactions: Ligand Molecular Arrays, SPR and NMR Methodologies.  |  Day, CJ., et al. 2017. Methods Mol Biol. 1512: 51-63. PMID: 27885598
  7. Mathermycin, a Lantibiotic from the Marine Actinomycete Marinactinospora thermotolerans SCSIO 00652.  |  Chen, E., et al. 2017. Appl Environ Microbiol. 83: PMID: 28576760
  8. Metabolites-Enabled Survival of Crucian Carps Infected by Edwardsiella tarda in High Water Temperature.  |  Jiang, M., et al. 2019. Front Immunol. 10: 1991. PMID: 31507599
  9. A family of radical halogenases for the engineering of amino-acid-based products.  |  Neugebauer, ME., et al. 2019. Nat Chem Biol. 15: 1009-1016. PMID: 31548692
  10. Highly Sensitive Amperometric α-Ketoglutarate Biosensor Based on Reduced Graphene Oxide-Gold Nanocomposites.  |  Peng, G., et al. 2020. Int J Anal Chem. 2020: 4901761. PMID: 32802061
  11. Detection of D-glutamate production from the dual Function enzyme, 4-amino-4-deoxychorismate Lyase/D-amino Acid Transaminase, in Mycobacterium smegmatis.  |  Opel-Reading, HK., et al. 2019. Bio Protoc. 9: e3135. PMID: 33654763
  12. Lysine acetylation restricts mutant IDH2 activity to optimize transformation in AML cells.  |  Chen, D., et al. 2021. Mol Cell. 81: 3833-3847.e11. PMID: 34289383
  13. Algorithm-aided engineering of aliphatic halogenase WelO5* for the asymmetric late-stage functionalization of soraphens.  |  Büchler, J., et al. 2022. Nat Commun. 13: 371. PMID: 35042883
  14. Peroxy Intermediate Drives Carbon Bond Activation in the Dioxygenase AsqJ.  |  Auman, D., et al. 2022. J Am Chem Soc. 144: 15622-15632. PMID: 35980821

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

α-Ketoglutaric acid sodium salt, 1 g

sc-214449
1 g
$39.00

α-Ketoglutaric acid sodium salt, 5 g

sc-214449A
5 g
$78.00