Date published: 2026-2-9

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α-D-Glucosamine Pentaacetate (CAS 7784-54-5)

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Alternate Names:
2-(Acetylamino)-2-deoxy-α-D-glucopyranose 1,3,4,6-Tetraacetate; 1,3,4,6-Tetra-O-acetyl-2-acetamido-2-deoxy-α-D-glucopyranose; N-Acetyl-α-D-glucosamine Tetraacetate
CAS Number:
7784-54-5
Molecular Weight:
389.35
Molecular Formula:
C16H23NO10
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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α-D-Glucosamine Pentaacetate is a chemically modified derivative of glucosamine, a naturally occurring amino sugar that is fundamental to the biosynthesis of glycosaminoglycans and glycoproteins. This derivative features five acetate groups, which protect the hydroxyl and amino functionalities, enhancing its stability and solubility in organic solvents, thus making it a valuable compound in organic synthesis and carbohydrate chemistry. In research, α-D-Glucosamine Pentaacetate is extensively used as a building block in the synthesis of complex oligosaccharides and glycoconjugates. The protection offered by the acetate groups allows for selective deprotection and functionalization, enabling the stepwise construction of more complex carbohydrate structures. This capability is particularly useful for studying carbohydrate-protein interactions, which are critical in numerous biological processes. Additionally, the use of this compound aids in understanding the chemical properties of glucosamine by altering its interaction dynamics with other biomolecules. It provides insights into the mechanisms of glycosylation reactions, helping to explain the roles of sugars in cellular communication and signaling in a purely scientific context. Through these applications, α-D-Glucosamine Pentaacetate contributes significantly to the field of glycoscience, enhancing our knowledge of carbohydrate chemistry and its implications.


α-D-Glucosamine Pentaacetate (CAS 7784-54-5) References

  1. Peracetylated 4-fluoro-glucosamine reduces the content and repertoire of N- and O-glycans without direct incorporation.  |  Barthel, SR., et al. 2011. J Biol Chem. 286: 21717-31. PMID: 21493714
  2. Rapid cyclic ion mobility separations of monosaccharide building blocks as a first step toward a high-throughput reaction screening platform for carbohydrate syntheses.  |  Peterson, TL. and Nagy, G. 2021. RSC Adv. 11: 39742-39747. PMID: 35494126
  3. Regeneration of amino functions from acetamidodeoxy sugars[M]//General Carbohydrate Method.  |  Hanessian S. 1972. Academic Press. 208-214.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

α-D-Glucosamine Pentaacetate, 2.5 g

sc-219469
2.5 g
$200.00