Molecular structure of α-Chlorocinnamaldehyde, CAS Number: 18365-42-9
α-Chlorocinnamaldehyde (CAS 18365-42-9)
CAS Number:
18365-42-9
Molecular Weight:
166.60
Molecular Formula:
C9H7ClO
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
α-Chlorocinnamaldehyde functions as an effective inhibitor of certain enzymes involved in cellular processes. α-Chlorocinnamaldehyde′s mechanism of action involves specific interactions with key amino acid residues within the enzyme′s active site, leading to conformational changes that impair its ability to carry out its normal biochemical function. This interference with enzyme activity can be leveraged to investigate the role of the targeted enzyme in various cellular pathways and processes. α-Chlorocinnamaldehyde plays a functional role in experimental applications by modulating enzyme activity and elucidating the molecular mechanisms underlying cellular processes.
α-Chlorocinnamaldehyde (CAS 18365-42-9) References
- Cinnamaldehyde and 2-methoxycinnamaldehyde as NF-kappaB inhibitors from Cinnamomum cassia. | Reddy, AM., et al. 2004. Planta Med. 70: 823-7. PMID: 15503352
- Inactivation of bovine plasma amine oxidase by haloallylamines. | Kim, J., et al. 2006. Bioorg Med Chem. 14: 1444-53. PMID: 16266805
- Alpha-substituted derivatives of cinnamaldehyde as tyrosinase inhibitors: inhibitory mechanism and molecular analysis. | Cui, Y., et al. 2015. J Agric Food Chem. 63: 716-22. PMID: 25547255
- Chiral Allenes via Alkynylogous Mukaiyama Aldol Reaction. | Tap, A., et al. 2016. Angew Chem Int Ed Engl. 55: 8962-5. PMID: 27275598
- Modifying effect of cinnamaldehyde and cinnamaldehyde derivatives on cell inactivation and cellular uptake of cis-diamminedichloroplatinum(II) in human NHIK 3025 cells. | Dornish, JM., et al. 1989. Cancer Res. 49: 3917-21. PMID: 2736532
- Halogenation Chemistry of Hydraulic Fracturing Additives under Highly Saline Simulated Subsurface Conditions. | Sumner, AJ. and Plata, DL. 2018. Environ Sci Technol. 52: 9097-9107. PMID: 30059203
- Halogen Radicals Contribute to the Halogenation and Degradation of Chemical Additives Used in Hydraulic Fracturing. | Chen, M., et al. 2021. Environ Sci Technol. 55: 1545-1554. PMID: 33449615
- Comparison on inhibitory effect and mechanism of inhibitors on sPPO and mPPO purified from 'Lijiang snow' peach by combining multispectroscopic analysis, molecular docking and molecular dynamics simulation. | Zhou, H., et al. 2023. Food Chem. 400: 134048. PMID: 36067690
- Effect of methyl and halogen substitutions in the αC position on the mutagenicity of cinnamaldehyde | T. Neudecker, K. Öhrlein, E. Eder, D. Henschler. 1983. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 110: 1-8.
- Synthesis and application of highly sensitive fluorescent probe for Hg2+ regulated by sulfur | Siyue Ma 1, Linyang Li 1, Mengyao She, Yan Mo, Shengyong Zhang, Ping Liu, Jianli Li. 2017. Chinese Chemical Letters. 28: 2014-2018.
- Synthesis and Antifungal Activities of Cinnamaldehyde Derivatives against Penicillium digitatum Causing Citrus Green Mold | Zengyu Gan,1Jianping Huang,2Jinyin Chen and,1,3Muhammad Farrukh Nisar,1,4,5and Wenwen Qi1. 2020. Biomaterials for Food Preservations. 2020.
- Improvement of mould resistance of wood with cinnamaldehyde chitosan emulsion | Zhenju Bi, Senmiao Fang, Qi Gao, Yafang Lei, Jeffrey J. Morrell & Li Yan. 2022. Wood Science and Technology. 56: 187–204.
- Synthesis, characterization, crystal structure, in silico and computational studies on a novel Schiff base derived from α-chlorocinnamaldehyde and 4-aminoantipyrine | Hillary Chijioke Adimudo a, Chidike Justus Agu a, Obinna U. Okenyeka a, Nnabuk O. Eddy a, Ebubechukwu Nnamdi Dim a, Necmi Dege c, Sebastian Bonardd d e, Kumar Vanka f g, Akachukwu Ibezim h, Digbo Iku Idika b, David Díaz Díaz d e, Nnamdi Lawrence Obasi a b. 2023. Journal of Molecular Structure. 1289.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
α-Chlorocinnamaldehyde, 1 g | sc-227161 | 1 g | $204.00 |