Date published: 2025-10-15

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α-Carotene (CAS 7488-99-5)

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Application:
α-Carotene is a control for HPLC
CAS Number:
7488-99-5
Purity:
≥95%
Molecular Weight:
536.87
Molecular Formula:
C40H56
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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α-Carotene is the second most common form of the orange photosynthetic pigment, carotene (β-carotene is the most common), and possesses a β-ring at one end and an ε-ring at the other. Humans and other mammals can produce retinal (a form of Vitamin A) from the retinyl group (β-ionone ring) of α-carotene, though its activity in this role is less than that of β-carotene, which has two retinyl groups. α-carotene is found in high concentrations in yellow-orange vegetables, such as carrots and squash, and dark-green vegetables, such as broccoli and spinach. High blood levels of α-carotene in adults has also been recently linked to lower mortality rates. It is useful as a control for HPLC.


α-Carotene (CAS 7488-99-5) References

  1. Lycopene cyclases determine high α-/β-carotene ratio and increased carotenoids in bananas ripening at high temperatures.  |  Fu, X., et al. 2019. Food Chem. 283: 131-140. PMID: 30722852
  2. Carrot Leaves Maintain Liver Vitamin A Concentrations in Male Mongolian Gerbils Regardless of the Ratio of α- to β-Carotene When β-Carotene Equivalents Are Equalized.  |  Titcomb, TJ., et al. 2019. J Nutr. 149: 951-958. PMID: 31050738
  3. Functional Identification of Two Types of Carotene Hydroxylases from the Green Alga Dunaliella bardawil Rich in Lutein.  |  Liang, MH., et al. 2020. ACS Synth Biol. 9: 1246-1253. PMID: 32408742
  4. Structural basis for plant lutein biosynthesis from α-carotene.  |  Niu, G., et al. 2020. Proc Natl Acad Sci U S A. 117: 14150-14157. PMID: 32513704
  5. Dietary β-Cryptoxanthin and α-Carotene Have Greater Apparent Bioavailability Than β-Carotene in Subjects from Countries with Different Dietary Patterns.  |  Olmedilla-Alonso, B., et al. 2020. Nutrients. 12: PMID: 32872544
  6. A Mechanistic Review of β-Carotene, Lutein, and Zeaxanthin in Eye Health and Disease.  |  Johra, FT., et al. 2020. Antioxidants (Basel). 9: PMID: 33114699
  7. Japanese carotenoid database with α- and β-carotene, β-cryptoxanthin, lutein, zeaxanthin, lycopene, and fucoxanthin and intake in adult women.  |  Fukushima, Y., et al. 2023. Int J Vitam Nutr Res. 93: 42-53. PMID: 33957770
  8. Mutation Associated with Orange Fruit Color Increases Concentrations of β-Carotene in a Sweet Pepper Variety (Capsicum annuum L.).  |  Tomlekova, N., et al. 2021. Foods. 10: PMID: 34071303
  9. Heterologous production of α-Carotene in Corynebacterium glutamicum using a multi-copy chromosomal integration method.  |  Li, C., et al. 2021. Bioresour Technol. 341: 125782. PMID: 34419880
  10. DcCCD4 catalyzes the degradation of α-carotene and β-carotene to affect carotenoid accumulation and taproot color in carrot.  |  Li, T., et al. 2021. Plant J. 108: 1116-1130. PMID: 34547154
  11. Relations between the Raman spectra and molecular structure of selected carotenoids: DFT study of α-carotene, β-carotene, γ-carotene and lycopene.  |  Novikov, VS., et al. 2022. Spectrochim Acta A Mol Biomol Spectrosc. 270: 120755. PMID: 34973611
  12. α-Carotene: a valuable carotenoid in biological and medical research.  |  Zhao, Z., et al. 2022. J Sci Food Agric. 102: 5606-5617. PMID: 35478460
  13. Differential hydroxylation efficiency of the two non-heme carotene hydroxylases: DcBCH1, rather than DcBCH2, plays a major role in carrot taproot.  |  Li, T., et al. 2022. Hortic Res. 9: uhac193. PMID: 36338853
  14. DsLCYB Directionally Modulated β-Carotene of the Green Alga Dunaliella salina under Red Light Stress.  |  Lan, Y., et al. 2022. J Microbiol Biotechnol. 32: 1622-1631. PMID: 36384973
  15. Association of Dietary α-Carotene and β-Carotene Intake with Low Cognitive Performance in Older Adults: A Cross-Sectional Study from the National Health and Nutrition Examination Survey.  |  Zhong, Q., et al. 2023. Nutrients. 15: PMID: 36615894

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

α-Carotene, 10 mg

sc-358725
10 mg
$570.00