Molecular structure of α,β-Methyleneadenosine 5′-triphosphate trisodium salt, CAS Number: 7292-42-4
α,β-Methyleneadenosine 5′-triphosphate trisodium salt (CAS 7292-42-4)
Alternate Names:
[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-[[hydroxy(phosphonooxy)phosphoryl]methyl]phosphinic acid
Application:
α,β-Methyleneadenosine 5′-triphosphate trisodium salt is a P2-purinoceptor agonist
CAS Number:
7292-42-4
Purity:
≥90%
Molecular Weight:
571.15
Molecular Formula:
C11H15N5Na3O12P3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
P2-purinoceptor agonist. Also shown to inhibit adenylate cyclase (Ki = 0.5 μM).
α,β-Methyleneadenosine 5′-triphosphate trisodium salt (CAS 7292-42-4) References
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- Purinergic P2X3 heteroreceptors enhance parasympathetic motor drive in isolated porcine detrusor, a reliable model for development of P2X selective blockers for detrusor hyperactivity. | D'Agostino, G., et al. 2012. Pharmacol Res. 65: 129-36. PMID: 22041665
- ADP-induced bladder contractility is mediated by P2Y12 receptor and temporally regulated by ectonucleotidases and adenosine signaling. | Yu, W., et al. 2014. FASEB J. 28: 5288-98. PMID: 25208846
- Expression and function of purinergic receptors in platelets from apheresis-derived platelet concentrates. | Koessler, J., et al. 2016. Blood Transfus. 14: 545-551. PMID: 26674810
- Biphasic Effect of ATP on In Vitro Mineralization of Dental Pulp Cells. | Techatharatip, O., et al. 2018. J Cell Biochem. 119: 488-498. PMID: 28598038
- ATP and astrocytes play a prominent role in the control of the respiratory pattern generator in the lamprey. | Cinelli, E., et al. 2017. J Physiol. 595: 7063-7079. PMID: 28734063
- Inhibitory effects of patchouli alcohol on stress-induced diarrhea-predominant irritable bowel syndrome. | Zhou, TR., et al. 2018. World J Gastroenterol. 24: 693-705. PMID: 29456408
- Human iPSC-derived trigeminal neurons lack constitutive TLR3-dependent immunity that protects cortical neurons from HSV-1 infection. | Zimmer, B., et al. 2018. Proc Natl Acad Sci U S A. 115: E8775-E8782. PMID: 30154162
- Sickle cell disease patient plasma sensitizes iPSC-derived sensory neurons from sickle cell disease patients. | Allison, RL., et al. 2023. bioRxiv.. PMID: 36711992
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P2X.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
α,β-Methyleneadenosine 5′-triphosphate trisodium salt, 1 mg | sc-204428 | 1 mg | $471.00 |