Date published: 2026-5-17

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α-Adenosine (CAS 5682-25-7)

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Alternate Names:
9-α-Ribofuranosyladenine
CAS Number:
5682-25-7
Purity:
≥85%
Molecular Weight:
267.24
Molecular Formula:
C10H13N5O4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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α-Adenosine, also known as adenosine or α-adenine riboside, is a nucleoside composed of the purine base adenine and the sugar ribose. It is naturally occurring in the body and plays various roles as a signaling molecule. α-Adenosine acts as a neurotransmitter and is involved in regulating numerous physiological processes, including sleep, cardiac function, immune response, and blood flow regulation.


α-Adenosine (CAS 5682-25-7) References

  1. Purification and characterization of intestinal adenosine deaminase from mice.  |  Singh, LS. and Sharma, R. 2000. Mol Cell Biochem. 204: 127-34. PMID: 10718633
  2. Adenosine deaminase in the adductor muscle of the scallop, Patinopecten yessoensis.  |  Sato, Y. and Aikawa, T. 1991. Comp Biochem Physiol B. 99: 221-32. PMID: 1959329
  3. The rate of spontaneous cleavage of the glycosidic bond of adenosine.  |  Stockbridge, RB., et al. 2010. Bioorg Chem. 38: 224-8. PMID: 20580404
  4. (31)P-MRS using visual stimulation protocols with different durations in healthy young adult subjects.  |  Barreto, FR., et al. 2014. Neurochem Res. 39: 2343-50. PMID: 25227748
  5. Bloch-Siegert B1+-mapping for human cardiac (31) P-MRS at 7 Tesla.  |  Clarke, WT., et al. 2016. Magn Reson Med. 76: 1047-58. PMID: 26509652
  6. Substrate specificity of human apurinic/apyrimidinic endonuclease APE1 in the nucleotide incision repair pathway.  |  Kuznetsova, AA., et al. 2018. Nucleic Acids Res. 46: 11454-11465. PMID: 30329131
  7. The Role of Active-Site Plasticity in Damaged-Nucleotide Recognition by Human Apurinic/Apyrimidinic Endonuclease APE1.  |  Bulygin, AA., et al. 2020. Molecules. 25: PMID: 32872297
  8. Functional Studies of α-Riboside Activation by the α-Ribazole Kinase (CblS) from Geobacillus kaustophilus.  |  Mattes, TA., et al. 2021. Biochemistry. 60: 2011-2021. PMID: 34105957
  9. Insights into Mechanisms of Damage Recognition and Catalysis by APE1-like Enzymes.  |  Bulygin, AA., et al. 2022. Int J Mol Sci. 23: PMID: 35457179
  10. Review of α-nucleosides: from discovery, synthesis to properties and potential applications.  |  Ni, G., et al. 2019. RSC Adv. 9: 14302-14320. PMID: 35519323
  11. Structural and enzymatic studies of a new analogue of coenzyme B12 with an alpha-adenosyl upper axial ligand.  |  Brown, KL., et al. 1998. Biochemistry. 37: 9704-15. PMID: 9657683
  12. Nucleosides and related substances: Part VI. The synthesis of 9-α-d-ribofuranosyladenine (α-adenosine)  |  Onodera, K., Hirano, S., & Masuda, F. 1967. Carbohydrate Research. 4(3): 263-266.
  13. Nuclear magnetic resonance and infrared spectroscopy examination of blood for diagnosis of the diffuse hepatopathy state  |  Kruchinina, M. V., Kruchinin, V. N., Shuvalov, G. V., Minin, I. V., & Minin, O. V. 2020. Optics and Spectroscopy. 128: 787-793.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

α-Adenosine, 5 mg

sc-214442
5 mg
$208.00