α-Actin Antibody (alpha-SM1): sc-130617
- α-Actin Antibody (alpha-SM1) is a mouse monoclonal IgG2a κ, cited in 69 publications, provided at 200 µg/ml
- raised against an N-terminal decapeptide of smooth muscle α-Actin of human origin
- recommended for detection of smooth muscle α-Actin of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; non cross-reactive with actin from fibroblasts (β-and γ-cytoplasmic), myocardium (α-myocardial), and striated muscle (α-sarcomeric)
- available conjugated to agarose for IP
- See α-Actin (1A4): sc-32251 for α-Actin antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG2a BP-HRP is the preferred secondary detection reagent for α-Actin Antibody (alpha-SM1) for WB and IHC(P) applications. This reagent is now offered in a bundle with α-Actin Antibody (alpha-SM1) (see ordering information below).
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SEE ALSO...
α-Actin Antibody (alpha-SM1) is a mouse monoclonal IgG2a antibody that detects α-Actin in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). α-Actin is a vital component of the cytoskeleton, playing a crucial role in maintaining cell shape, enabling cellular movement, and facilitating muscle contraction. α-Actin is predominantly found in muscle tissues, where α-Actin forms part of the contractile apparatus, but α-Actin is also present in non-muscle cells, contributing to the structural integrity of the cell. The presence of multiple isoforms of Actin, such as α-, β-, and γ-Actin, allows for specialized functions in different cell types, with α-Actin being essential for muscle function. The regulation of α-Actin is influenced by various signaling pathways, including those involving small GTPases, which orchestrate the dynamic organization of the Actin cytoskeleton. Understanding the function and regulation of α-Actin is critical, as alterations in α-Actin expression or organization can lead to various diseases, including cardiomyopathies and other muscle-related disorders. With broad reactivity and versatility in applications, anti-α-Actin antibody (alpha-SM1) is an invaluable tool for researchers studying the intricate roles of Actin in cellular processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
α-Actin Antibody (alpha-SM1) | sc-130617 | 200 µg/ml | $316.00 | |||
α-Actin Antibody (alpha-SM1): m-IgG2a BP-HRP Bundle | sc-546020 | 200 µg Ab; 10 µg BP | $354.00 | |||
α-Actin Antibody (alpha-SM1) AC | sc-130617 AC | 500 µg/ml, 25% agarose | $416.00 |