Molecular structure of Almotriptan Malate
Almotriptan Malate (CAS 181183-52-8)
Alternate Names:
1-[[[2-(Dimethyl-amino)ethyl]-1H-indol-5-yl]methyl]sulfonyl]pyrrolidine Malate
Application:
Almotriptan Malate is a serotonin 5HT1B /1D-receptor agonist used for treatment of migraines
CAS Number:
181183-52-8
Molecular Weight:
469.55
Molecular Formula:
C17H25N3O2S•C4H6O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Almotriptan Malate is a serotonin 5HT1B /1D-receptor agonist used for treatment of migraines.
Almotriptan Malate (CAS 181183-52-8) References
- Oral almotriptan vs. oral sumatriptan in the abortive treatment of migraine: a double-blind, randomized, parallel-group, optimum-dose comparison. | Spierings, EL., et al. 2001. Arch Neurol. 58: 944-50. PMID: 11405809
- Use of rescue medication in trials of almotriptan versus placebo in the treatment of acute migraine. | Mathew, NT. 2002. Clin Ther. 24: 520-9. PMID: 12017397
- A validated reversed phase HPLC method for the determination of process-related impurities in almotriptan malate API. | Kumar, AP., et al. 2008. J Pharm Biomed Anal. 46: 792-8. PMID: 18191357
- Almotriptan, an antimigraine agent, and its malate salt. | Ravikumar, K., et al. 2008. Acta Crystallogr C. 64: o15-7. PMID: 18216450
- Development and Validation of HPTLC Method for the Estimation of Almotriptan Malate in Tablet Dosage Form. | Suneetha, A. and Syamasundar, B. 2010. Indian J Pharm Sci. 72: 629-32. PMID: 21694997
- Effect of iontophoresis on in vitro transdermal absorption of almotriptan. | Calatayud-Pascual, MA., et al. 2011. Int J Pharm. 416: 189-94. PMID: 21736929
- Method development and validation of almotriptan in human plasma by HPLC tandem mass spectrometry: application to pharmacokinetic study. | Ravikumar, K., et al. 2012. Sci Pharm. 80: 367-78. PMID: 22896823
- Migraine therapeutics in adolescents: a systematic analysis and historic perspectives of triptan trials in adolescents. | Sun, H., et al. 2013. JAMA Pediatr. 167: 243-9. PMID: 23359002
- Pharmaceutical salts: a summary on doses of salt formers from the Orange Book. | Saal, C. and Becker, A. 2013. Eur J Pharm Sci. 49: 614-23. PMID: 23747999
- High performance liquid chromatographic analysis of almotriptan malate in bulk and tablets. | Lavudu, P., et al. 2013. Adv Pharm Bull. 3: 183-8. PMID: 24312833
- Gellan gum-based mucoadhesive microspheres of almotriptan for nasal administration: Formulation optimization using factorial design, characterization, and in vitro evaluation. | Abbas, Z. and Marihal, S. 2014. J Pharm Bioallied Sci. 6: 267-77. PMID: 25400410
- A novel nasal almotriptan loaded solid lipid nanoparticles in mucoadhesive in situ gel formulation for brain targeting: Preparation, characterization and in vivo evaluation. | Youssef, NAHA., et al. 2018. Int J Pharm. 548: 609-624. PMID: 30033394
- Migraine Patients With Cardiovascular Disease and Contraindications: An Analysis of Real-World Claims Data. | Dodick, DW., et al. 2020. J Prim Care Community Health. 11: 2150132720963680. PMID: 33095099
- Intranasal delivery of nanostructured lipid carriers, solid lipid nanoparticles and nanoemulsions: A current overview of in vivo studies. | Costa, CP., et al. 2021. Acta Pharm Sin B. 11: 925-940. PMID: 33996407
- In Vivo Evaluation of Almotriptan malate Formulation through Intranasal Route for the Treatment of Migraine: Systematic Development and Pharmacokinetic Assessment. | Gupta, S., et al. 2023. AAPS PharmSciTech. 24: 32. PMID: 36627414
Activator of:
SR-1B.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Almotriptan Malate, 10 mg | sc-396219 | 10 mg | $360.00 |