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Allyl chloride (CAS 107-05-1)

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Alternate Names:
3-Chloro-1-propene; Chlorallylene
Application:
Allyl chloride is a chlorinated derivative of propylene used as an alkylating agent
CAS Number:
107-05-1
Molecular Weight:
76.52
Molecular Formula:
C3H5Cl
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Available in US only.
* Refer to Certificate of Analysis for lot specific data.

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Allyl chloride is an organic compound. It manifests as a colorless, highly flammable liquid with a distinctive acrid odor. It serves as a reagent in organic synthesis and polymer production. The scientific research realm widely employs allyl chloride across various applications. As a reagent, it aids in organic synthesis and contributes to polymer synthesis. Notably, allyl chloride plays a vital role in the synthesis of allyl alcohol, allyl acetate, and allyl amines. In terms of reactivity, allyl chloride is an electrophilic reagent that readily engages with nucleophiles such as alcohols, amines, and carboxylic acids. This reaction follows a nucleophilic substitution mechanism, replacing the chlorine atom with the incoming nucleophile.


Allyl chloride (CAS 107-05-1) References

  1. Bioassay of allyl chloride for possible carcinogenicity.  |  ,. 1978. Natl Cancer Inst Carcinog Tech Rep Ser. 73: 1-115. PMID: 12830224
  2. Vapor toxicity of allyl chloride as determined on laboratory animals.  |  TORKELSON, TR., et al. 1959. Am Ind Hyg Assoc J. 20: 217-23. PMID: 13661078
  3. Allyl chloride-induced time dependent changes of lipid peroxidation in rat nerve tissue.  |  Wang, QS., et al. 2005. Neurochem Res. 30: 1387-95. PMID: 16341935
  4. Allyl chloride: the mutagenic activity of its photooxidation products.  |  Shepson, PB., et al. 1987. Environ Sci Technol. 21: 568-73. PMID: 19994977
  5. A Review on Mutagenicity Testing for Hazard Classification of Chemicals at Work: Focusing on in vivo Micronucleus Test for Allyl Chloride.  |  Rim, KT. and Kim, SJ. 2015. Saf Health Work. 6: 184-91. PMID: 26929826
  6. Total synthesis of (-)-kainic acid and (+)-allo-kainic acid through SmI2-mediated intramolecular coupling between allyl chloride and an α,β-unsaturated ester.  |  Suzuki, J., et al. 2017. Org Biomol Chem. 15: 6557-6566. PMID: 28748237
  7. Total Syntheses of C60- and C100-Dolichols.  |  Hirao, K., et al. 2020. J Org Chem. 85: 11549-11559. PMID: 32786646
  8. Genetic activity of allyl chloride.  |  McCoy, EC., et al. 1978. Mutat Res. 57: 11-5. PMID: 347285
  9. Using Compound Specific Isotope Analysis to decipher the 1,2,3-trichloropropane-to-Allyl chloride transformation by groundwater microbial communities.  |  Zhang, M., et al. 2023. Environ Pollut. 316: 120577. PMID: 36336183
  10. The acute toxicity of allyl chloride by subcutaneous injection in mice.  |  Omura, M., et al. 1993. Fukuoka Igaku Zasshi. 84: 427-32. PMID: 8225155
  11. Biotransformation of allyl chloride in the rat. Influence of inducers on the urinary metabolic profile.  |  de Rooij, BM., et al. 1996. Drug Metab Dispos. 24: 765-72. PMID: 8818574
  12. Allylmercapturic acid as urinary biomarker of human exposure to allyl chloride.  |  de Rooij, BM., et al. 1997. Occup Environ Med. 54: 653-61. PMID: 9423578

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Allyl chloride, 500 ml

sc-214524
500 ml
$48.00
US: Only available in the US

Allyl chloride, 1 L

sc-214524A
1 L
$82.00
US: Only available in the US