Date published: 2026-4-14

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Allethrin (CAS 584-79-2)

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Alternate Names:
Allylcinerin
Application:
Allethrin is a synthetic compound that modulates sodium channels in the nerve cell membrane
CAS Number:
584-79-2
Molecular Weight:
302.4
Molecular Formula:
C19H26O3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Allethrin is a type I pyrethroid, useful as a very weakly active "negative" control for inhibition of calcineurin (protein phosphatase 2B) by type II pyrethroids.


Allethrin (CAS 584-79-2) References

  1. Specific inhibition of calcineurin by type II synthetic pyrethroid insecticides.  |  Enan, E. and Matsumura, F. 1992. Biochem Pharmacol. 43: 1777-84. PMID: 1315545
  2. Nerve membrane Na+ channels as targets of insecticides.  |  Narahashi, T. 1992. Trends Pharmacol Sci. 13: 236-41. PMID: 1321523
  3. Allethrin-induced genotoxicity and oxidative stress in Swiss albino mice.  |  Srivastava, AK., et al. 2012. Mutat Res. 747: 22-28. PMID: 22475934
  4. Allethrin toxicity on human corneal epithelial cells involves mitochondrial pathway mediated apoptosis.  |  Gupta, G., et al. 2013. Toxicol In Vitro. 27: 2242-8. PMID: 24055895
  5. Allethrin induces oxidative stress, apoptosis and calcium release in rat testicular carcinoma cells (LC540).  |  Madhubabu, G. and Yenugu, S. 2014. Toxicol In Vitro. 28: 1386-95. PMID: 25072698
  6. Allethrin toxicity causes reproductive dysfunction in male rats.  |  Madhubabu, G. and Yenugu, S. 2017. Environ Toxicol. 32: 1701-1710. PMID: 28181402
  7. Allethrin and prallethrin stimulates MUC5AC expression through oxidative stress in human airway epithelial cells.  |  Na, HG., et al. 2018. Biochem Biophys Res Commun. 503: 316-322. PMID: 29885834
  8. Mechanism of allethrin biodegradation by a newly isolated Sphingomonas trueperi strain CW3 from wastewater sludge.  |  Bhatt, P., et al. 2020. Bioresour Technol. 305: 123074. PMID: 32146283
  9. Binding interaction of allethrin with esterase: Bioremediation potential and mechanism.  |  Bhatt, P., et al. 2020. Bioresour Technol. 315: 123845. PMID: 32707504
  10. Novel mechanism and degradation kinetics of allethrin using Bacillus megaterium strain HLJ7 in contaminated soil/water environments.  |  Huang, Y., et al. 2022. Environ Res. 214: 113940. PMID: 35952736

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Allethrin, 10 mg

sc-202921
10 mg
$32.00

Allethrin, 25 mg

sc-202921A
25 mg
$43.00