Date published: 2026-4-1

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Allantoin (CAS 97-59-6)

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Alternate Names:
5-Ureidohydantoin; Glyoxylic(acid) diureide
Application:
Allantoin is a purine metabolite for biochemical research
CAS Number:
97-59-6
Purity:
≥98%
Molecular Weight:
158.12
Molecular Formula:
C4H6N4O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Allantoin, a naturally occurring compound, manifests as a white, odorless powder with a crystalline structure. Its solubility in water and ethanol makes it highly versatile. The primary mode of action of allantoin involves the stimulation of keratinocyte production. Allantoin is a purine metabolite via the uric acid pathway


Allantoin (CAS 97-59-6) References

  1. Allantoin as a vitamin.  |  Gus'kov, EP., et al. 2004. Dokl Biochem Biophys. 398: 320-4. PMID: 15584519
  2. Final report of the safety assessment of allantoin and its related complexes.  |  Becker, LC., et al. 2010. Int J Toxicol. 29: 84S-97S. PMID: 20448269
  3. Allantoin and hydantoin as new protein aggregation suppressors.  |  Nishinami, S., et al. 2018. Int J Biol Macromol. 114: 497-503. PMID: 29505874
  4. Allantoin improves histopathological evaluations in a rat model of gastritis.  |  Eslami-Farsani, M., et al. 2018. Physiol Int. 105: 325-334. PMID: 30582339
  5. TLC-densitometric analysis of allantoin in Symphytum officinale L. roots.  |  Kimel, K., et al. 2020. Acta Pharm. 70: 101-110. PMID: 31677368
  6. Exogenous allantoin improves the salt tolerance of sugar beet by increasing putrescine metabolism and antioxidant activities.  |  Liu, L., et al. 2020. Plant Physiol Biochem. 154: 699-713. PMID: 32750647
  7. Exogenous allantoin improves anthocyanin accumulation in grape berry skin at early stage of ripening.  |  Moriyama, A., et al. 2020. J Plant Physiol. 253: 153253. PMID: 32828011
  8. Biosynthesis of allantoin in Escherichia coli via screening a highly effective urate oxidase.  |  Zhang, F., et al. 2022. Biotechnol Bioeng. 119: 2518-2528. PMID: 35488433
  9. Allantoin overaccumulation enhances production of metabolites under excess of metals but is not tightly regulated by nitric oxide.  |  Dresler, S., et al. 2022. J Hazard Mater. 436: 129138. PMID: 35617731
  10. Allantoin ameliorates amyloid β-peptide-induced memory impairment by regulating the PI3K/Akt/GSK-3β signaling pathway in rats.  |  Tzeng, CY., et al. 2022. Biomed Pharmacother. 153: 113389. PMID: 36076477
  11. Combined Metabolomic and Transcriptomic Analysis Reveals Allantoin Enhances Drought Tolerance in Rice.  |  Lu, S., et al. 2022. Int J Mol Sci. 23: PMID: 36430648
  12. Allantoin induces pruritus by activating MrgprD in chronic kidney disease.  |  Yang, Y., et al. 2023. J Cell Physiol. 238: 813-828. PMID: 36879552
  13. Allantoin improves salinity tolerance in Arabidopsis and rice through synergid activation of abscisic acid and brassinosteroid biosynthesis.  |  Chowrasia, S., et al. 2023. Plant Mol Biol. 112: 143-160. PMID: 37184674

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Allantoin, 25 g

sc-207271
25 g
$42.00

Allantoin, 100 g

sc-207271A
100 g
$57.00