(all-Z)-6,9,12,15,18-Heneicosapentaenoic Acid (CAS 24257-10-1)

(all-Z)-6,9,12,15,18-Heneicosapentaenoic acid, also known as HPA, is a polyunsaturated fatty acid (PUFA) with five cis double bonds, making it structurally similar to eicosapentaenoic acid (EPA). This compound is of significant interest in research due to its unique structural properties and biological activities. HPA is utilized in studies investigating the role of long-chain PUFAs in cell membrane dynamics, signaling pathways, and metabolic processes. The presence of multiple cis double bonds in HPA confers high fluidity to lipid bilayers, influencing membrane properties such as permeability, elasticity, and protein function. Researchers use HPA to explore its effects on lipid metabolism and its incorporation into phospholipids, which are essential components of cellular membranes. Studies have demonstrated that HPA can modulate the activity of enzymes involved in fatty acid desaturation and elongation, providing insights into the regulatory mechanisms of lipid biosynthesis. Additionally, HPA is employed in research examining its role in signal transduction pathways, particularly those mediated by lipid-derived mediators such as eicosanoids. Overall, (all-Z)-6,9,12,15,18-Heneicosapentaenoic acid is a crucial compound in lipidomics and membrane biology research, offering valuable insights into the complex roles of PUFAs in cellular function and metabolism.