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all-trans Retinoic Acid-d5 (CAS 302-79-4 (unlabeled))

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Alternate Names:
Aberel-d5; Avita-d5; Retin-A-d5; Retinova-d5
Application:
all-trans Retinoic Acid-d5 is an isotopically labeled analog of retinoic acid
CAS Number:
302-79-4 (unlabeled)
Molecular Weight:
305.47
Molecular Formula:
C20H23D5O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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all-trans Retinoic Acid-d5 is an isotopically labeled form of all-trans retinoic acid, a metabolite of vitamin A, used extensively in biochemical and analytical research. The deuterium atoms in the compound provide a stable isotope label that enables precise tracking and quantification of all-trans retinoic acid in experimental studies. It is used as an internal standard in mass spectrometry to ensure accurate measurements in complex biological samples, aiding in the understanding of retinoic acid′s role in cellular signaling pathways. Researchers also use all-trans Retinoic Acid-d5 to investigate the compound′s involvement in gene regulation and its impact on cell differentiation and proliferation. Additionally, this labeled variant is instrumental in studying the kinetics and metabolism of retinoic acid in various biological systems.


all-trans Retinoic Acid-d5 (CAS 302-79-4 (unlabeled)) References

  1. Vitamin A regulates Akt signaling through the phospholipid fatty acid composition.  |  Pein, H., et al. 2017. FASEB J. 31: 4566-4577. PMID: 28687611
  2. Carotenoid intake and SCD genotype exert complementary effects over fat content and fatty acid composition in Duroc pigs.  |  Henriquez-Rodriguez, E., et al. 2017. J Anim Sci. 95: 2547-2557. PMID: 28727051
  3. Isotretinoin administration improves sperm production in men with infertility from oligoasthenozoospermia: a pilot study.  |  Amory, JK., et al. 2017. Andrology. 5: 1115-1123. PMID: 28980413
  4. Quantification of All-Trans Retinoic Acid by Liquid Chromatography-Tandem Mass Spectrometry and Association with Lipid Profile in Patients with Type 2 Diabetes.  |  Morgenstern, J., et al. 2021. Metabolites. 11: PMID: 33478094
  5. Retinoic acid regulates pyruvate dehydrogenase kinase 4 (Pdk4) to modulate fuel utilization in the adult heart: Insights from wild-type and β-carotene 9',10' oxygenase knockout mice.  |  Holloway, C., et al. 2022. FASEB J. 36: e22513. PMID: 36004605

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

all-trans Retinoic Acid-d5, 1 mg

sc-217605
1 mg
$516.00

all-trans Retinoic Acid-d5, 10 mg

sc-217605A
10 mg
$3823.00

What are the shipping conditions?

Asked by: SCchem16
Thank you for your question. This chemical, all-trans Retinoic Acid-d5: sc-217605, will ship dry for both domestic and international shipping.
Answered by: Chemical Support 2
Date published: 2017-04-05
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Rated 5 out of 5 by from Various publications cite the use of allVarious publications cite the use of all-trans Retinoic Acid-d5 to track its activity, both in vitro and in vivo. -SCBT Publication Review
Date published: 2015-03-08
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all-trans Retinoic Acid-d5 is rated 5.0 out of 5 by 1.
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