ALL-SIL Whole Cell Lysate: sc-364356

The ALL-SIL Whole Cell Lysate is derived from a specific line of human acute lymphoblastic leukemia cells, known for its applications in basic cancer biology research. This lysate is a critical resource, providing a complex mixture of proteins, RNA, and other cellular constituents extracted from leukemia cells. Originating from a patient-derived leukemia cell line, ALL-SIL represents an invaluable model for studying the cellular and molecular framework of leukemia cells under various experimental conditions. Researchers use this lysate to delve deeply into the cellular machinery of leukemia, exploring aspects such as signal transduction pathways, cellular proliferation, and apoptosis mechanisms. By comparing the protein expression profiles and genetic markers in the ALL-SIL lysate to those in healthy lymphoid cells, scientists can identify key differences and interactions that may play roles in the pathology of leukemia. Moreover, the lysate is extensively used in molecular biology techniques, including Western blotting, ELISA, and mass spectrometry, which facilitate the identification and quantification of cellular components. This aids in understanding the biochemical cascades and regulatory networks that are active in leukemia cells, thereby providing insights into the fundamental processes that govern cell behavior in this disease state.