Date published: 2026-3-12

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Aldicarb-sulfone (CAS 1646-88-4)

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CAS Number:
1646-88-4
Molecular Weight:
222.26
Molecular Formula:
C7H14N2O4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Aldicarb-sulfone is a chemical compound that functions as an acetylcholinesterase inhibitor. It acts by irreversibly binding to the active site of the enzyme, preventing the breakdown of the neurotransmitter acetylcholine. This inhibition leads to an accumulation of acetylcholine at the synaptic cleft, resulting in continuous stimulation of the postsynaptic receptors. At the molecular level, aldircarb-sulfone disrupts the normal transmission of nerve impulses, ultimately leading to paralysis and death of the target organism. Aldicarb-Sulfone′s mechanism of action involves interfering with the normal functioning of the nervous system, making it useful for studying the physiological and biochemical processes involved in neurotransmission.


Aldicarb-sulfone (CAS 1646-88-4) References

  1. Determination of aldicarb, aldicarb sulfoxide and aldicarb sulfone in some fruits and vegetables using high-performance liquid chromatography-atmospheric pressure chemical ionization mass spectrometry.  |  Nunes, GS., et al. 2000. J Chromatogr A. 888: 113-20. PMID: 10949478
  2. Extraction of aldicarb and its metabolites from excreta and gastrointestinal tissue.  |  Harper, FD., et al. 1998. Anal Chem. 70: 3329-32. PMID: 11013730
  3. Nonlethal method for forensic evaluation of aldicarb exposure in wildlife.  |  Cobb, GP., et al. 2001. Arch Environ Contam Toxicol. 40: 77-88. PMID: 11116343
  4. Assessment of leaching potential of aldicarb and its metabolites using laboratory studies.  |  Fava, L., et al. 2001. Pest Manag Sci. 57: 1135-41. PMID: 11802601
  5. Effects of four carbamate compounds on antioxidant parameters.  |  Maran, E., et al. 2009. Ecotoxicol Environ Saf. 72: 922-30. PMID: 18328561
  6. Accelerated degradation of aldicarb and its metabolites in cotton field soils.  |  Lawrence, KS., et al. 2005. J Nematol. 37: 190-7. PMID: 19262860
  7. In-Vitro and In-Vivo Effects of Aldicarb on Survival and Development of Heterodera schachtii.  |  Steele, AE. and Hodges, LR. 1975. J Nematol. 7: 305-12. PMID: 19308173
  8. Behavioral Responses of Heterodera rostochiensis Larvae to Aldicarb and its Sulfoxide and Sulfone.  |  Nelmes, AJ. 1970. J Nematol. 2: 223-7. PMID: 19322301
  9. [Determination of aldicarb and its metabolites in peanuts by high performance liquid chromatography-linear ion trap triple stage mass spectrometry].  |  Yang, X., et al. 2012. Se Pu. 30: 309-13. PMID: 22715699
  10. [Analysis of aldicarb and its metabolites in ginger using ultra performance liquid chromatography-tandem mass spectrometry coupled with multiplug filtration clean up with multiwalled carbon nanotubes].  |  Ma, L., et al. 2014. Se Pu. 32: 635-9. PMID: 25269263
  11. Acute toxicity of aldicarb, aldicarb sulfoxide, and aldicarb sulfone to Daphnia laevis.  |  Foran, JA., et al. 1985. Bull Environ Contam Toxicol. 35: 546-50. PMID: 4052657
  12. Aldicarb sulfoxide/aldicarb sulfone mixture in drinking water of rats: effects on growth and acetylcholinesterase activity.  |  DePass, LR., et al. 1985. J Toxicol Environ Health. 16: 163-72. PMID: 4078930
  13. Kinetics of aqueous base and acid hydrolysis of aldicarb, aldicarb sulfoxide and aldicarb sulfone.  |  Lemley, AT. and Zhong, WZ. 1983. J Environ Sci Health B. 18: 189-206. PMID: 6853962
  14. High pressure chromatography determination of aldicarb, aldicarb sulfoxide, and aldicarb sulfone in potatoes.  |  Cochrane, WP. and Lanouette, M. 1981. J Assoc Off Anal Chem. 64: 724-8. PMID: 7240079
  15. Determination of aldicarb, aldicarb sulfoxide and aldicarb sulfone in tobacco using high-performance liquid chromatography with dual post-column reaction and fluorescence detection.  |  Yang, SS. and Smetena, I. 1994. J Chromatogr A. 664: 289-94. PMID: 8199709

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Aldicarb-sulfone, 100 mg

sc-252354
100 mg
$138.00