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Alcian Yellow (CAS 61968-76-1)

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Alternate Names:
Ingrain Yellow 1
CAS Number:
61968-76-1
Molecular Weight:
838.03
Molecular Formula:
C40H46N8S42Cl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Alcian Yellow is a diazo dye that plays a critical role in histological staining protocols, particularly in the differentiation of tissue types. In research, it is applied to study the mucin content within tissue sections, where it selectively binds to certain glycoprotein components, enabling researchers to visualize and distinguish cellular structures under the microscope. Its application is in the field of pathology, where it helps elucidate the morphology of gastrointestinal tissues, often in combination with other dyes like Alcian Blue in a dual-staining technique. The compound′s interaction with tissue elements is further investigated to refine staining methods and improve diagnostic specificity. In addition to its staining capabilities, Alcian Yellow is also utilized in materials science research, where its adsorption properties are used to analyze the surface chemistry of polymers designed to mimic biological tissues.


Alcian Yellow (CAS 61968-76-1) References

  1. Immunocytochemical localization of insulin-related peptide(s) in the central nervous system of the snail Helix aspersa Müller: involvement in growth control.  |  Gomot, A., et al. 1992. Cell Mol Neurobiol. 12: 21-32. PMID: 1373991
  2. ALCIAN BLUE-ALCIAN YELLOW: A NEW METHOD FOR THE IDENTIFICATION OF DIFFERENT ACIDIC GROUPS.  |  CARLO, R. 1964. J Histochem Cytochem. 12: 44-5. PMID: 14187307
  3. Alcian yellow as a fluorescent dye.  |  Stockert, JC., et al. 1989. Acta Histochem. 85: 59-63. PMID: 2496573
  4. Alcian blue-alcian yellow mapping of neurosecretory cells in the central nervous system of the salt marsh pulmonate snail Melampus bidentatus.  |  Ridgway, RL. 1987. Comp Biochem Physiol A Comp Physiol. 87: 295-303. PMID: 2886270
  5. Investigations of dye binding in the sequential staining of mucosaccharides by Alcian Yellow-Alcian Blue. II. Spot tests and experiments on dye-mucopolysaccharide (glycosaminoglycan) precipitates.  |  Sorvari, TE. and Näntö, V. 1971. Histochem J. 3: 269-77. PMID: 4108050
  6. [Observations on the staining of acid mucopolysaccharides with the Alcian blue-Alcian yellow method in the salivary glands].  |  Siervo, R., et al. 1965. Riv Ital Stomatol. 20: 630-41. PMID: 4157666
  7. Demonstration of biologic polyanions by alcian blue in salt solutions and by alcian yellow or hexadecylpyridinium-hexathiocyanatoferrate.  |  Staple, PH. 1967. J Histochem Cytochem. 15: 552-4. PMID: 4168051
  8. The specificity of Alcian Blue pH 1.0-Alcian Yellow pH 2.5 staining in the histochemical differentiation of acidic groups in mucosubstances.  |  Sorvari, TE. and Sorvari, RM. 1969. J Histochem Cytochem. 17: 291-3. PMID: 4183946
  9. Environmental osmolarity and neurosecretory neurones in Lymnaea stagnalis (L.).  |  Soffe, SR., et al. 1979. Malacologia. 18: 583-6. PMID: 491760
  10. A comparative study on neurosecretion demonstrated by the alcian blue-alcian yellow technique in three terrestrial pulmonates (Stylommatophora).  |  Wijdenes, J., et al. 1980. Cell Tissue Res. 210: 47-56. PMID: 6157474
  11. Neurosecretory cells in the central nervous system of Helicella virgata (Gastropoda, Pulmonata).  |  Ottaviani, E. and Franchini, A. 1982. Z Mikrosk Anat Forsch. 96: 583-90. PMID: 7180080
  12. A novel Alcian yellow-toluidine blue (Leung) stain for Helicobacter species: comparison with standard stains, a cost-effectiveness analysis, and supplemental utilities.  |  Vartanian, RK., et al. 1998. Mod Pathol. 11: 72-8. PMID: 9556427
  13. Correspondence re: Vartanian RK, Leung JK, Davis JE, Kim YB, Owen DA: A novel alcian yellow-toluidine blue (Leung) stain for Helicobacter species: comparison with standard stains, a cost-effectiveness analysis, and supplemental utilities. Mod Pathol 1998;11:72-8.  |  Carr, NJ. and Owens, EW. 1998. Mod Pathol. 11: 798. PMID: 9720512

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Alcian Yellow, 1 g

sc-291851B
1 g
$89.00

Alcian Yellow, 5 g

sc-291851
5 g
$351.00

Alcian Yellow, 25 g

sc-291851A
25 g
$1282.00