Akt2 Antibody (8B7): sc-81436
- Akt2 Antibody (8B7) is a mouse monoclonal IgG2a, cited in 8 publications, provided at 50 µg/0.5 ml
- raised against amino acids 107-123 of Akt2 of human origin
- recommended for detection of Akt2 of mouse, rat and human origin by WB, IP and IF
- See Akt2 (F-7): sc-5270 for Akt2 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Akt2 Antibody (8B7). This work is in progress.
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Akt2 Antibody (8B7) is a mouse monoclonal IgG2a antibody that detects Akt2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Akt2, also known as PKBβ, plays a crucial role in various cellular processes, including glucose metabolism, cell survival, and proliferation, making Akt2 a key player in the insulin signaling pathway. Akt2 is primarily located in the cytoplasm and translocates to the plasma membrane upon activation, where Akt2 interacts with phosphatidylinositol 3,4,5-trisphosphate, a lipid product of phosphatidylinositol 3-kinase. The membrane localization of Akt2 is essential for activation by upstream kinases, which phosphorylate Akt2 on specific residues, allowing signal cascade propagation that influences cellular growth and metabolism. Dysregulation of Akt2 has been implicated in several diseases, including cancer and metabolic disorders, highlighting Akt2′s importance as a therapeutic target. Anti-Akt2 antibody (8B7) is an invaluable tool for researchers studying these pathways and Akt2′s role in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Akt2 Antibody (8B7) | sc-81436 | 50 µg/0.5 ml | $316.00 |