Molecular structure of Agelongine, CAS Number: 163564-84-9
Agelongine (CAS 163564-84-9)
Application:
Agelongine is a serotonin receptor antagonist
CAS Number:
163564-84-9
Molecular Weight:
339.1
Molecular Formula:
C13H11BrN2O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Agelongine is a bromopyrrole pyridinium alkaloid isolated from the Agelas longissima sea sponge. Agelongine is described to exhibit antiserotonergic effects on rat stomach fundus strip, demonstrating specific shifting of the 5-HT (Serotonin, sc-201146) concentration-response curve in this system. The antagonism of 5-HT by Agelongine is demonstrated to be reversible.
Agelongine (CAS 163564-84-9) References
- Inhibition of cyclin-dependent kinases, GSK-3beta and CK1 by hymenialdisine, a marine sponge constituent. | Meijer, L., et al. 2000. Chem Biol. 7: 51-63. PMID: 10662688
- Dominicin, a cyclic octapeptide, and laughine, a bromopyrrole alkaloid, isolated from the Caribbean marine sponge Eurypon laughlini. | Williams, DE., et al. 2005. J Nat Prod. 68: 327-30. PMID: 15787430
- Bromopyrrole alkaloids as lead compounds against protozoan parasites. | Scala, F., et al. 2010. Mar Drugs. 8: 2162-74. PMID: 20714430
- Bioactive pyrrole alkaloids isolated from the Red Sea: marine sponge Stylissa carteri. | Hamed, ANE., et al. 2018. Z Naturforsch C J Biosci. 73: 199-210. PMID: 29353267
- Novel bromopyrrole alkaloids from the sponge Agelas dispar. | Cafieri, F., et al. 1998. J Nat Prod. 61: 122-5. PMID: 9461661
- Novel betaines from the marine sponge Agelas dispar. | Cafieri, F., et al. 1998. J Nat Prod. 61: 1171-3. PMID: 9748394
- A novel bromopyrrole alkaloid from the sponge Agelas longissima with antiserotonergic activity. | Cafieri, Francesco, et al. 1995. Bioorganic & Medicinal Chemistry Letters. 5.8: 799-804.
- Anti-histaminic activity of bromopyrrole alkaloids isolated from Caribbean Agelas sponges. | Cafieri, Francesco, et al. 1997. Bioorganic & Medicinal Chemistry Letters. 7.17: 2283-2288.
- Agelamadin F and tauroacidin E, bromopyrrole alkaloids from an Okinawan marine sponge Agelas sp. | Kusama, Taishi, et al. 2015. Tetrahedron letters. 56.30: 4502-4504.
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Agelongine, 1 mg | sc-202447 | 1 mg | $109.00 |