AFMK CAS: 52450-38-1
MF: C13H16N2O4
MW: 264.28
An immunomodulatory antioxidant melatonin metabolite.

AFMK (CAS 52450-38-1)

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Alternate Names: N-[3-[2-(formylamino)-5-methoxyphenyl]-3-oxypropyl]-acetamide; NSC 688263
Application: AFMK is an immunomodulatory antioxidant melatonin metabolite
CAS Number: 52450-38-1
Purity: >98%
Molecular Weight: 264.28
Molecular Formula: C13H16N2O4
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

AFMK is a metabolite of the pineal hormone melatonin that exhibits antioxidant, immunomodulatory and anti-inflammatory properties. AFMK was first detected in rat brain and was found to be useful as an index for melatonin synthesis and metabolism.


References

1. Harthé, C., et al. 2003. Life Sci. 73: 1587-1597. PMID: 12865098
2. Silva, S.O., et al. 2004. J. Neuroimmunol. 156: 146-152. PMID: 15465605
3. Manda, K., et al. 2007. J. Pineal Res. 42: 386-393. PMID: 17439555
4. Ximenes, V.F. 2008. J. Pineal Res. 45: 297-301. PMID: 18373552
5. Manda, K., et al. 2008. J. Pineal Res. 45: 430-438. PMID: 18631288

Physical State :
Solid
Solubility :
Soluble in ethanol (~5 mg/ml), DMSO (~30 mg/ml), DMF (~30 mg/ml), methanol, and water (1 mg/ml at 25° C).
Storage :
Store at -20° C
Melting Point :
123-126° C
Boiling Point :
~589.4° C at 760 mmHg (Predicted)
Density :
~1.2 g/cm3 (Predicted)
Refractive Index :
n20D 1.56 (Predicted)
pK Values :
pKa: 13.79 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
171161
MDL Number :
MFCD02683241
SMILES :
CC(=O)NCCC(=O)C1=C(C=CC(=C1)OC)NC=O

Download SDS (MSDS)

Certificate of Analysis

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What is the shipping temperature of this product?

Asked by: hawkeye11
This chemical, AFMK (CAS 52450-38-1), ships ambient.
Answered by: Chemical Support 1
Date published: 2017-03-24
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