AFAP-1L1 Antibody (D-7): sc-376700
- AFAP-1L1 Antibody (D-7) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 651-755 mapping near the C-terminus of AFAP-1L1 of human origin
- recommended for detection of AFAP-1L1 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for AFAP-1L1 Antibody (D-7) for WB applications. This reagent is now offered in a bundle with AFAP-1L1 Antibody (D-7) (see ordering information below).
AFAP-1L1 Antibody (D-7) is a mouse monoclonal IgG1 antibody that detects AFAP-1L1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). AFAP-1L1, a 768 amino acid protein, plays a crucial role in cellular signaling and actin organization, functioning as an adaptor protein that links signaling molecules to actin filaments. This interaction is vital for the formation of larger signaling complexes, which are essential for the activation of Src kinases in response to various cellular signals. Notably, AFAP-1L1 is phosphorylated upon DNA damage, likely by the ataxia-telangiectasia mutated (ATM) or ATM and Rad3-related (ATR) kinases, highlighting AFAP-1L1′s importance in cellular responses to stress. Additionally, AFAP-1L1 exists in four isoforms due to alternative splicing, which may contribute to AFAP-1L1′s functional diversity and regulatory mechanisms within the cell. Anti-AFAP-1L1 antibody (D-7) is an invaluable tool for researchers studying the intricate roles of AFAP-1L1 in actin dynamics and cellular signaling pathways.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
AFAP-1L1 Antibody (D-7) | sc-376700 | 200 µg/ml | $322.00 | |||
AFAP-1L1 Antibody (D-7): m-IgG Fc BP-HRP Bundle | sc-540633 | 200 µg Ab; 10 µg BP | $361.00 |