Date published: 2025-10-2

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ADX-47273 (CAS 851881-60-2)

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Application:
ADX-47273 is potent and selective metabotropic glutamate receptor 5 allosteric modulator
CAS Number:
851881-60-2
Molecular Weight:
369.36
Molecular Formula:
C20H17F2N3O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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ADX-47273 is a novel, potent and selective metabotropic glutamate receptor 5 allosteric modulator with an EC50 of 170 nM. ADX-47273 shifted mGlu5 receptor glutamate response curve to the left. ADX-47273 elevated extracellular signal-regulated kinase and cAMP-responsive element-binding protein phosphorylation in hippocampus and prefrontal cortex.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

ADX-47273, 5 mg

sc-364397
5 mg
$433.00

ADX-47273, 10 mg

sc-364397A
10 mg
$764.00