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ADX-47273 is a novel, potent and selective metabotropic glutamate receptor 5 allosteric modulator with an EC50 of 170 nM. ADX-47273 shifted mGlu5 receptor glutamate response curve to the left. ADX-47273 elevated extracellular signal-regulated kinase and cAMP-responsive element-binding protein phosphorylation in hippocampus and prefrontal cortex.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ADX-47273, 5 mg | sc-364397 | 5 mg | $433.00 | |||
ADX-47273, 10 mg | sc-364397A | 10 mg | $764.00 |