Date published: 2026-4-1

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Adrenosterone (CAS 382-45-6)

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Alternate Names:
11-Ketoandrostenedione; 4-Androstene-3,11,17-trione; Androst-4-ene-3;11,17-trione; Reichstein′s substance G
CAS Number:
382-45-6
Purity:
≥97%
Molecular Weight:
300.39
Molecular Formula:
C19H24O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Adrenosterone is an endogenous steroid hormone and belongs to the group of glucocorticoids. It is as a precursor for cortisol. Adrenosterone is a strong mineralocorticoid and contributes to the regulation of blood pressure, electrolyte balance, and water balance within the body.


Adrenosterone (CAS 382-45-6) References

  1. Biotransformation of adrenosterone by filamentous fungus, Cunninghamella elegans.  |  Choudhary, MI., et al. 2007. Steroids. 72: 923-9. PMID: 17889091
  2. Urinary metabonomics study on biochemical changes in an experimental model of chronic renal failure by adenine based on UPLC Q-TOF/MS.  |  Zhao, YY., et al. 2012. Clin Chim Acta. 413: 642-9. PMID: 22227165
  3. Multiple mechanisms of ligand interaction with the human organic cation transporter, OCT2.  |  Harper, JN. and Wright, SH. 2013. Am J Physiol Renal Physiol. 304: F56-67. PMID: 23034939
  4. Tandem mass spectrometry approach for the investigation of the steroidal metabolism: structure-fragmentation relationship (SFR) in anabolic steroids and their metabolites by ESI-MS/MS analysis.  |  Musharraf, SG., et al. 2013. Steroids. 78: 171-81. PMID: 23159734
  5. Total synthesis of starfish saponin goniopectenoside B.  |  Xiao, G. and Yu, B. 2013. Chemistry. 19: 7708-12. PMID: 23649953
  6. Pathways and genes involved in steroid hormone metabolism in male pigs: a review and update.  |  Robic, A., et al. 2014. J Steroid Biochem Mol Biol. 140: 44-55. PMID: 24239507
  7. Regio- and stereospecific hydroxylation of various steroids at the 16α position of the D ring by the Streptomyces griseus cytochrome P450 CYP154C3.  |  Makino, T., et al. 2014. Appl Environ Microbiol. 80: 1371-9. PMID: 24334658
  8. Isaria fumosorosea KCh J2 Entomopathogenic Strain as an Effective Biocatalyst for Steroid Compound Transformations.  |  Kozłowska, E., et al. 2017. Molecules. 22: PMID: 28891949
  9. Hydroxylation of Steroids by a Microbial Substrate-Promiscuous P450 Cytochrome (CYP105D7): Key Arginine Residues for Rational Design.  |  Ma, B., et al. 2019. Appl Environ Microbiol. 85: PMID: 31540985
  10. A Novel Zebrafish Model of Metastasis Identifies the HSD11β1 Inhibitor Adrenosterone as a Suppressor of Epithelial-Mesenchymal Transition and Metastatic Dissemination.  |  Nakayama, J., et al. 2020. Mol Cancer Res. 18: 477-487. PMID: 31748280
  11. 17β-Hydroxysteroid dehydrogenase type 12 is responsible for maturation-inducing steroid synthesis during oocyte maturation in Nile tilapia.  |  Aranyakanont, C., et al. 2020. Gen Comp Endocrinol. 290: 113399. PMID: 31982399
  12. Xmrks the Spot: Fish Models for Investigating Epidermal Growth Factor Receptor Signaling in Cancer Research.  |  Monroe, JD., et al. 2021. Cells. 10: PMID: 34067095
  13. Spontaneous conversion of prenyl halides to acids: application in metal-free preparation of deuterated compounds under mild conditions.  |  Darshana, D., et al. 2021. Org Biomol Chem. 19: 7390-7402. PMID: 34296730
  14. Gastrulation Screening to Identify Anti-metastasis Drugs in Zebrafish Embryos.  |  Nakayama, J., et al. 2022. Bio Protoc. 12: PMID: 36313195
  15. Development of mass spectrometry-based methods for the detection of 11-ketotestosterone and 11-ketodihydrotestosterone.  |  Piper, T. and Thevis, M. 2023. Drug Test Anal.. PMID: 36652270

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Adrenosterone, 5 g

sc-233824
5 g
$260.00

Adrenosterone, 25 g

sc-233824A
25 g
$1200.00

Adrenosterone, 100 g

sc-233824B
100 g
$4000.00