Adrenochrome (CAS 54-06-8)

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Alternate Names: 3-Hydroxy-1-methyl-5,6-indolinedione; 2,3-dihydro-3-hydroxy-1-methyl-1H-indole-5,6-dione

Application: Adrenochrome is an inhibitor of catechol-o-methyltransferase

CAS Number: 54-06-8

Molecular Weight: 179.17

Molecular Formula: C₉H₉NO₃

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

* Refer to Certificate of Analysis for lot specific data (including water content).

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Adrenochrome is an oxidation product of adrenaline (ephinephrine, norepinephrine). It inhibits COMT (Catechol-O-methyltransferase), promotes the synthesis of prostaglandins in brain tissue in vitro, promotes the secretion of nerve growth factor by L-M ce.

References

1. Costa, V.M., et al. 2007. Chem. Res. Toxicol., 20: 1183-1191. PMID: 17630707
2. Sotomayor-Zarate, R., et al. 2008. Biol. Reprod. 78: 673-680. PMID: 18077802

Physical State :

Solid

Solubility :

Soluble in water (0.3 mg/ml), ethanol, and 1 M sodium hydroxide (50 mg/ml, gives a dark brown solution).

Storage :

Store at -20° C

Melting Point :

125° C

Boiling Point :

~375.1° C at 760 mmHg (Predicted)

Density :

~1.4 g/cm³ (Predicted)

Refractive Index :

n²⁰_D 1.63 (Predicted)

pK Values :

pK_a: 13.31 (Predicted), pK_b: 3.3 (Predicted)

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

WGK Germany :

RTECS :

NM1925000

PubChem CID :

5898

Merck Index :

14: 172

MDL Number :

MFCD00069732

EC Number :

200-192-8

SMILES :

CN1CC(C2=CC(=O)C(=O)C=C21)O

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Certificate of Analysis

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Adrenochrome (CAS 54-06-8) Product Citations

See how others have used Adrenochrome (CAS 54-06-8). Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 22426700 Gelain, DP. et al. 2012. Acta Pharmacol. Sin. 33: 558-567.

Citations 1 to 1 of 1 total

What is Adrenochrome used for, and what are the natural sources?

Asked by: L DMEM

Thank you for your question. Adrenochrome acts as an inhibitor of catechol-o-methyltransferase. The native source is synthetic.

Answered by: Tech Service

Date published: 2020-04-23

Rated 5 out of 5 by JvZ1986 from Just terrific! I bought it a couple of months ago and am so happy that I did! Thanks!

Date published: 2019-03-26

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