AdrenochromeCAS: 54-06-8
MF: C9H9NO3
MW: 179.17
An inhibitor of catechol-o-methyltransferase.

Adrenochrome (CAS 54-06-8)

Adrenochrome | CAS 54-06-8 is rated 5.0 out of 5 by 1.
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Synonym: 3-Hydroxy-1-methyl-5,6-indolinedione; 2,3-dihydro-3-hydroxy-1-methyl-1H-indole-5,6-dione
Application: An inhibitor of catechol-o-methyltransferase
CAS Number: 54-06-8
Molecular Weight: 179.17
Molecular Formula: C9H9NO3
* Refer to Certificate of Analysis for lot specific data (including water content).
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Adrenochrome is an oxidation product of adrenaline (ephinephrine, norepinephrine). It inhibits COMT (Catechol-O-methyltransferase), promotes the synthesis of prostaglandins in brain tissue in vitro, promotes the secretion of nerve growth factor by L-M ce.


References

1. Costa, V.M., et al. 2007. Chem. Res. Toxicol., 20: 1183-1191. PMID: 17630707
2. Sotomayor-Zarate, R., et al. 2008. Biol. Reprod. 78: 673-680. PMID: 18077802

Physical State :
Solid
Solubility :
Soluble in water (0.3 mg/ml), ethanol, and 1 M sodium hydroxide (50 mg/ml, gives a dark brown solution).
Storage :
Store at -20° C
Melting Point :
125° C
Boiling Point :
~375.1° C at 760 mmHg (Predicted)
Density :
~1.4 g/cm3 (Predicted)
Refractive Index :
n20D 1.63 (Predicted)
pK Values :
pKa: 13.31 (Predicted), pKb: 3.3 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
NM1925000
PubChem CID :
5898
Merck Index :
14: 172
MDL Number :
MFCD00069732
EC Number :
200-192-8
SMILES :
CN1CC(C2=CC(=O)C(=O)C=C21)O

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Certificate of Analysis

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Adrenochrome  Product Citations

See how others have used Adrenochrome. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 22426700  Gelain, DP. et al. 2012. Acta Pharmacol. Sin. 33: 558-567.

Citations 1 to 1 of 1 total

What is Adrenochrome used for, and what are the natural sources?

Asked by: L DMEM
Thank you for your question. Adrenochrome acts as an inhibitor of catechol-o-methyltransferase. The native source is synthetic.
Answered by: Tech Service
Date published: 2019-10-10
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Rated 5 out of 5 by from Just terrific! I bought it a couple of months ago and am so happy that I did! Thanks!
Date published: 2019-03-26
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