Molecular structure of Adrafinil, CAS Number: 63547-13-7
Adrafinil (CAS 63547-13-7)
Alternate Names:
Olmifon; 2-benzhydrylsulfinyl-N-hydroxyacetamide
Application:
Adrafinil is an α-adrenergic agonist
CAS Number:
63547-13-7
Molecular Weight:
289.35
Molecular Formula:
C15H15NO3S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Adrafinil is AR (alpha-Adrenergic) agonist. Adrafinil undergoes metabolic conversion to generate modafinil. In vitro investigations have been conducted to explore the impact of adrafinil on various biochemical pathways, unveiling its ability to influence several neurotransmitter systems such as dopamine, serotonin, and norepinephrine. Adrafinil acts as a selective, weak, atypical dopamine reuptake inhibitor, which indirectly leads to an increase in neurotransmitter activity. Furthermore, adrafinil has demonstrated the capacity to modulate the cholinergic system, which plays a role in processes related to learning and memory.
Adrafinil (CAS 63547-13-7) References
- Oral administration of adrafinil improves discrimination learning in aged beagle dogs. | Milgram, NW., et al. 2000. Pharmacol Biochem Behav. 66: 301-5. PMID: 10880682
- Adrafinil disrupts performance on a delayed nonmatching-to-position task in aged beagle dogs. | Siwak, CT., et al. 2003. Pharmacol Biochem Behav. 76: 161-8. PMID: 13679229
- LC-ESI-MS determination and pharmacokinetics of adrafinil in rats. | Rao, RN., et al. 2008. J Chromatogr B Analyt Technol Biomed Life Sci. 873: 119-23. PMID: 18723408
- Enantioselective separation and determination of adrafinil and modafinil on Chiralcel OJ-H column in rat serum and urine using solid-phase extraction followed by HPLC. | Rao, RN. and Shinde, DD. 2009. Biomed Chromatogr. 23: 811-6. PMID: 19353685
- Effects of single and repeated treatment with antidepressants on apomorphine-induced yawning in the rat: the implication of alpha-1 adrenergic mechanisms in the D-2 receptor function. | Delini-Stula, A. and Hunn, C. 1990. Psychopharmacology (Berl). 101: 62-6. PMID: 1971448
- Evaluation of antitussive activity of formulations with herbal extracts in sulphur dioxide (SO2) induced cough model in mice. | Gupta, YK., et al. 2009. Indian J Physiol Pharmacol. 53: 61-6. PMID: 19810578
- A novel study of screening and confirmation of modafinil, adrafinil and their metabolite modafinilic acid under EI-GC-MS and ESI-LC-MS-MS ionization. | Dubey, S., et al. 2009. Indian J Pharmacol. 41: 278-83. PMID: 20407560
- Fluorescent zinc and copper complexes for detection of adrafinil in paper-based microfluidic devices. | Caglayan, MG., et al. 2016. Chem Commun (Camb). 52: 8279-82. PMID: 27293080
- Effect of modafinil on pancreatic exocrine secretion in rats. A comparison with adrafinil and related drugs. | Chariot, J., et al. 1987. Fundam Clin Pharmacol. 1: 243-52. PMID: 2893764
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AR.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Adrafinil, 10 mg | sc-207263 | 10 mg | $285.00 | |||
Adrafinil, 100 mg | sc-207263A | 100 mg | $725.00 |