ADM Antibody (HTA171/E8): sc-53153

ADM Antibody (HTA171/E8) is a mouse monoclonal IgM antibody that detects adrenomedullin (ADM) in human samples through applications such as immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). ADM is a crucial vasodilator produced by various contractile cells, playing a significant role in regulating fluid and electrolyte balance as well as maintaining cardiovascular health. Anti-ADM antibody (HTA171/E8) recognizes ADM in the vascular endothelium and adrenal medulla, where ADM is secreted into the bloodstream to exert systemic effects. This localization enables ADM to act quickly on target tissues, influencing renal function and promoting natriuresis, which is the excretion of sodium in urine. ADM enhances glomerular filtration rate while reducing sodium reabsorption in the distal tubules, underscoring ADM′s importance in fluid homeostasis and blood pressure regulation. ADM has been shown to have central effects, including the modulation of appetite, highlighting ADM′s multifaceted role in both peripheral and central physiological processes. With diverse functions and critical involvement in cardiovascular health, ADM monoclonal antibody (HTA171/E8) serves as an essential tool for researchers studying adrenomedullin′s implications in various physiological and pathological contexts.