Molecular structure of Adenylyl(3′ 5′)cytidine, CAS Number: 2382-66-3
Adenylyl(3′ 5′)cytidine (CAS 2382-66-3)
Alternate Names:
Adenylyl-3'-5'-D-cytidine
Application:
Adenylyl(3′ 5′)cytidine is an adenosine-containing dinucleotide
CAS Number:
2382-66-3
Purity:
≥98%
Molecular Weight:
572.42
Molecular Formula:
C19H25N8O11P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Adenylyl(3′ 5′)cytidine is an adenosine-containing dinucleotide which is beneficial for the survival and proliferation of neurofibroma (NF1). Alternates show that Adenylyl(3′ 5′)cytidine binds to ribonuclease-A in a manner that is different than uridylyl-3′,5′-adenosine. The cytidine moiety of the molecule can bind to the B1 and R1 sites on the enzyme, while the phosphate group binds to the non-specific site and the adenosine portion is not in a fixed position.
Adenylyl(3′ 5′)cytidine (CAS 2382-66-3) References
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- Addressing the challenge of changing the specificity of RNase T1 with rational and evolutionary approaches. | Struhalla, M., et al. 2004. Chembiochem. 5: 200-5. PMID: 14760741
- RNase T1 variant RV cleaves single-stranded RNA after purines due to specific recognition by the Asn46 side chain amide. | Czaja, R., et al. 2004. Biochemistry. 43: 2854-62. PMID: 15005620
- Sequence-dependent emission from stacked forms of ApC and CpA. Evidence for stacked base ('dimer') absorption and left-handed stacked conformation. | Daniels, M., et al. 1988. Biophys Chem. 32: 229-37. PMID: 3251569
- The enzymic synthesis of adenylyl-(3'-5')-cytidine. | Zhenodarova, SM. and Habarova, MI. 1968. Biochim Biophys Acta. 169: 559-60. PMID: 4302872
- Purification and characterization of bovine aorta ribonucleases. | Lewis R GAMBLE, W. 1969. Biochem J. 115: 95-101. PMID: 5346373
- Studies on the binding of adenylyl-3', 5'-cytidine to ribonuclease. | Mitsui, Y., et al. 1978. Biochim Biophys Acta. 535: 299-308. PMID: 678553
- Growth-promoting action of adenosine-containing dinucleotide on neuroblastoma cells: detection of adenosine-cytidine dinucleotide (ApCp) in neurofibroma (NF1) extracts. | Hotta, T., et al. 1993. J Neurochem. 61: 1430-7. PMID: 8376996
- Reactivity and selectivity in light-induced free radical reactions of 2-propanol with purine and pyrimidine mononucleotides and dinucleoside monophosphates. | Havron, A., et al. 1976. Nucleic Acids Res. 3: 1715-25. PMID: 967670
- The effect of stacking on a low‐frequency vibrational band in an aqueous solution of adenylyl‐3′, 5′‐cytidine (ApC) | Nielsen, O. F., Christensen, D. H., Aubard, J., & Dodin, G. 1984. Journal of Raman spectroscopy. 15(2): 134-136.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Adenylyl(3' 5')cytidine, 2 mg | sc-221218 | 2 mg | $1100.00 |