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Adenosine 5′-diphosphate sodium salt (CAS 20398-34-9)

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Alternate Names:
ADP
Application:
CAS Number:
20398-34-9
Purity:
≥95%
Molecular Weight:
427.20
Molecular Formula:
C10H15N5O10P2•xNa
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Adenosine 5′-diphosphate sodium salt is an adenine nucleotide that is phosphorylated into ATP by ATPase. This phosphorylation is a key part of cellular homeostatis as it allows for energy storage and is involved in nucleic acid metabolism. ADP affects platelet activation through its interaction with ADP receptors P2Y1, P2Y12 and P2X1. Upon its conversion to adenosine by ecto-ADPases, platelet activation is inhibited via adenosine receptors.


Adenosine 5′-diphosphate sodium salt (CAS 20398-34-9) References

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  2. Europium tetracycline as a luminescent probe for nucleoside phosphates and its application to the determination of kinase activity.  |  Schäferling, M. and Wolfbeis, OS. 2007. Chemistry. 13: 4342-9. PMID: 17323391
  3. Usefulness of delta value of platelet parameters on ADVIA 120 for the functional reactivity of stored platelets.  |  Park, IJ., et al. 2010. J Clin Lab Anal. 24: 38-43. PMID: 20087952
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  6. Platelet-derived growth factor receptor-α-positive cells and not smooth muscle cells mediate purinergic hyperpolarization in murine colonic muscles.  |  Kurahashi, M., et al. 2014. Am J Physiol Cell Physiol. 307: C561-70. PMID: 25055825
  7. Generation of procoagulant collagen- and thrombin-activated platelets in platelet concentrates derived from buffy coat: the role of processing, pathogen inactivation, and storage.  |  Bertaggia Calderara, D., et al. 2018. Transfusion. 58: 2395-2406. PMID: 30229925
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  9. Acute nociception mediated by hindpaw P2X receptor activation in the rat.  |  Bland-Ward, PA. and Humphrey, PP. 1997. Br J Pharmacol. 122: 365-71. PMID: 9313948
  10. Mechanisms underlying reduced P2Y1-receptor-mediated relaxation in superior mesenteric arteries from long-term streptozotocin-induced diabetic rats  |  Ishida, K., Matsumoto, T., Taguchi, K., Kamata, K., & Kobayashi, T. 2013. Acta Physiologica. 207(1): 130-141.
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  12. Mapping the Separation Landscape of Pharmaceuticals: Rapid and Efficient Scale-Up of Preparative Purifications Enabled by Computer-Assisted Chromatographic Method Development  |  Bennett, R., Haidar Ahmad, I. A., DaSilva, J., Figus, M., Hullen, K., Tsay, F. R.,.. & Regalado, E. L. 2019. Organic Process Research & Development. 23(12): 2678-2684.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Adenosine 5′-diphosphate sodium salt, 100 mg

sc-210761
100 mg
$63.00

Adenosine 5′-diphosphate sodium salt, 500 mg

sc-210761A
500 mg
$80.00

Adenosine 5′-diphosphate sodium salt, 1 g

sc-210761B
1 g
$139.00

Adenosine 5′-diphosphate sodium salt, 1 kg

sc-210761C
1 kg
$3934.00